Document Detail

Prognostic value of initial subtype in schizophrenic disorders.
MedLine Citation:
PMID:  8043525     Owner:  NLM     Status:  MEDLINE    
The prognostic value of the subtype diagnosis at the initial episode was investigated in 148 narrowly defined schizophrenic patients. Every initial episode was classified according to multiple criteria: DSM-III-R, ICD-10, the positive/negative dichotomy, and Schneider's first rank symptoms. Patients were followed up on average 23 years later (range 10-50 years). Different aspects of long-term outcome were evaluated (global functioning, social adjustment, negative social consequences). In 93% of the patients persisting alterations were found at the end of the observation time. The influence of the predominant clinical features at the initial episode on various aspects of long-term outcome was found to differ depending on which of the four diagnostic systems was used. The highest power for discrimination was found for the subtypes of DSM-III-R, while the presence of first rank symptoms had no prognostic value. It was found that patients with an initial paranoid or positive episode had a significantly better long-term outcome than patients initially having a disorganised/hebephrenic or catatonic episode. The frequency of negative social consequences was not influenced by the initial subtype, with the exception of permanent hospitalisation.
A Deister; A Marneros
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Schizophrenia research     Volume:  12     ISSN:  0920-9964     ISO Abbreviation:  Schizophr. Res.     Publication Date:  1994 May 
Date Detail:
Created Date:  1994-08-31     Completed Date:  1994-08-31     Revised Date:  2010-09-02    
Medline Journal Info:
Nlm Unique ID:  8804207     Medline TA:  Schizophr Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  145-57     Citation Subset:  IM    
Psychiatric Department, University of Bonn, Germany.
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MeSH Terms
Delusions / psychology,  rehabilitation
Depression / psychology,  rehabilitation
Hallucinations / psychology,  rehabilitation
Middle Aged
Psychiatric Status Rating Scales
Schizophrenia / classification*,  diagnosis,  rehabilitation
Schizophrenic Psychology*
Social Adjustment*

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