Document Detail


Prognostic value of initial subtype in schizophrenic disorders.
MedLine Citation:
PMID:  8043525     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The prognostic value of the subtype diagnosis at the initial episode was investigated in 148 narrowly defined schizophrenic patients. Every initial episode was classified according to multiple criteria: DSM-III-R, ICD-10, the positive/negative dichotomy, and Schneider's first rank symptoms. Patients were followed up on average 23 years later (range 10-50 years). Different aspects of long-term outcome were evaluated (global functioning, social adjustment, negative social consequences). In 93% of the patients persisting alterations were found at the end of the observation time. The influence of the predominant clinical features at the initial episode on various aspects of long-term outcome was found to differ depending on which of the four diagnostic systems was used. The highest power for discrimination was found for the subtypes of DSM-III-R, while the presence of first rank symptoms had no prognostic value. It was found that patients with an initial paranoid or positive episode had a significantly better long-term outcome than patients initially having a disorganised/hebephrenic or catatonic episode. The frequency of negative social consequences was not influenced by the initial subtype, with the exception of permanent hospitalisation.
Authors:
A Deister; A Marneros
Related Documents :
17959255 - Clinical characteristics of patients with gender identity disorder at a japanese gender...
14594915 - Chromosome 22q11 deletions, velo-cardio-facial syndrome and early-onset psychosis. mole...
20498135 - Metabolic parameters in patients treated with olanzapine or other atypical antipsychotics.
9134595 - Patients with deficit, nondeficit, and negative symptom schizophrenia: do they differ d...
8995745 - Proximal tubular injury in chinese herbs nephropathy: monitoring by neutral endopeptida...
19255845 - Impact of capsule endoscopy findings in the management of crohn's disease.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Schizophrenia research     Volume:  12     ISSN:  0920-9964     ISO Abbreviation:  Schizophr. Res.     Publication Date:  1994 May 
Date Detail:
Created Date:  1994-08-31     Completed Date:  1994-08-31     Revised Date:  2010-09-02    
Medline Journal Info:
Nlm Unique ID:  8804207     Medline TA:  Schizophr Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  145-57     Citation Subset:  IM    
Affiliation:
Psychiatric Department, University of Bonn, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Attention
Delusions / psychology,  rehabilitation
Depression / psychology,  rehabilitation
Female
Hallucinations / psychology,  rehabilitation
Humans
Male
Middle Aged
Prognosis
Psychiatric Status Rating Scales
Schizophrenia / classification*,  diagnosis,  rehabilitation
Schizophrenic Psychology*
Social Adjustment*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cortical cholinergic markers in schizophrenia.
Next Document:  Premorbid adjustment in schizophrenia: implications for psychosocial and ventricular pathology.