Document Detail


Prognostic value of electrocardiographic criteria for left ventricular hypertrophy.
MedLine Citation:
PMID:  16084164     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Many electrocardiographic (ECG) criteria for left ventricular hypertrophy (LVH) exist, but few studies have compared their relative prognostic value for predicting cardiovascular (CV) mortality. METHODS: We analyzed the first ECG on 46950 consecutive veterans. We targeted male outpatients with a body mass index > 20 to avoid confounding by complicating catabolic illnesses and further excluded those with conduction abnormalities. Using Cox regression models adjusted for age, heart rate, and body mass index, we compared the hazard ratios (HRs) for CV mortality obtained from seventeen commonly used ECG criteria for LVH. RESULTS: During a mean follow-up of 7 +/- 4 years, in a total population of 19434 patients (mean age 54 +/- 14 years), 1254 (6%) patients died of CV causes. The adjusted HR for CV mortality ranged from 1.4 (95% CI 1.2-1.6) to 3.7 (95% CI 2.7-5.0) among the various criteria. Left ventricular hypertrophy defined by composite criteria was generally associated with higher adjusted HRs compared with voltage-only criteria. Among patients with ECG-LVH, the presence of a left ventricular strain pattern or increased negative P-terminal force were most predictive of CV mortality (HR 3.9 and 3.5, 95% CI 3.3-4.6 and 2.8-4.2). CONCLUSIONS: Compared with voltage-only criteria for detecting LVH, composite ECG criteria are more strongly predictive of CV mortality. By applying these ECG criteria into routine clinical practice, individuals with LVH who are at higher risk for CV mortality can be identified and appropriately treated.
Authors:
Bill P Hsieh; Michael X Pham; Victor F Froelicher
Related Documents :
17347694 - Intravascular volume dependency of left ventricular mass calculation by two-dimensional...
18498814 - Longitudinal study of the profile and predictors of left ventricular mass regression af...
14671464 - Relationship of electrocardiographic left ventricular hypertrophy to mortality and card...
19390744 - Association of angiotensin-converting enzyme activity and polymorphism with echocardiog...
24276094 - Electrocardiography series. electrocardiographic t wave abnormalities.
17198774 - Effect of intravenous n-acetylcysteine on outcomes after coronary artery bypass surgery...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  150     ISSN:  1097-6744     ISO Abbreviation:  Am. Heart J.     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2005-08-08     Completed Date:  2005-11-28     Revised Date:  2006-02-27    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  161-7     Citation Subset:  AIM; IM    
Affiliation:
Division of Cardiovascular Medicine, Stanford University School of Medicine, VA Palo Alto Health Care System, Palo Alto, CA 94304, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Electrocardiography*
Humans
Hypertrophy, Left Ventricular / diagnosis*,  mortality*
Male
Middle Aged
Prognosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Depressed autonomic nervous system function in African Americans and individuals of lower social cla...
Next Document:  Left ventricular diastolic function in normotensive subjects 2 months after acute myocardial infarct...