| Prognostic value and diagnostic potential of cardiopulmonary exercise testing in patients with chronic heart failure. | |
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MedLine Citation:
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PMID: 18255336 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cardiopulmonary exercise testing (CPET) is a well established technique for stratifying cardiovascular risk in patients with chronic heart failure (CHF). Important prognostic variables include a reduced peak oxygen uptake which has a central use in cardiac transplant selection, and the abnormal relation between minute ventilation (VE) and carbon dioxide production (VCO(2)), often referred to as the elevated VE/VCO(2) slope. We will discuss the pathophysiology of these abnormal responses to exercise in CHF, and how these are interpreted during CPET. The potential of CPET for diagnosing circulatory, respiratory, metabolic, musculoskeletal or mixed limitations is an emerging field of research. We will speculate on how CHF manifests during CPET, and clarify the pathophysiological basis of these exercise responses. To improve our understanding of the diagnostic value of CPET, further investigation is required by clinicians to develop reference ranges for CHF patients from a co-ordinated multicentre approach. The use of CPET technology is becoming increasingly prevalent in cardiology services, and it is likely that, in the future, CPET will take a more prominent role in guiding patient management provision. |
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Authors:
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Lee Ingle |
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Publication Detail:
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Type: Journal Article; Review Date: 2008-02-05 |
Journal Detail:
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Title: European journal of heart failure Volume: 10 ISSN: 1388-9842 ISO Abbreviation: Eur. J. Heart Fail. Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-02-18 Completed Date: 2008-05-28 Revised Date: 2011-06-08 |
Medline Journal Info:
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Nlm Unique ID: 100887595 Medline TA: Eur J Heart Fail Country: Netherlands |
Other Details:
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Languages: eng Pagination: 112-8 Citation Subset: IM |
Affiliation:
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Carnegie Faculty of Sport and Education, Leeds Metropolitan University, Beckett's Park, Headingley, Leeds LS6 3QS, UK. L.Ingle@leedsmet.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anaerobic Threshold Chronic Disease Exercise / physiology Exercise Test* Exercise Tolerance / physiology Heart Failure / complications, diagnosis*, physiopathology* Humans Oxygen Consumption Prognosis Respiratory Insufficiency / etiology, physiopathology Risk Assessment |
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