| Prognostic value of computed tomography coronary angiography in patients with suspected coronary artery disease: a 24-month follow-up study. | |
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MedLine Citation:
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PMID: 19224218 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to determine the predictive value of 64-slice computed tomography coronary angiography (CTCA) for major cardiac events in patients with suspected coronary artery disease (CAD). A total of 187 consecutive patients (119 men, age 62.5 +/- 10.5 years) without known heart disease underwent single-source 64-slice CTCA (Somatom Sensation 64, Siemens) for clinical suspicion of CAD. Patients underwent follow-up for the occurrence of cardiac death, nonfatal myocardial infarction, unstable angina and cardiac revascularization. In total, 2,822 coronary segments were assessed. Forty-two segments (1.5%) were not assessable because of insufficient image quality. Overall, CTCA revealed absence of CAD in 65 (34.7%) patients, nonobstructive CAD (coronary plaque < or =50%) in 87 (46.5%) patients and obstructive CAD (>50%) in 35 (18.8%) patients. A total of 20 major cardiac events (3 myocardial infarctions, 16 cardiac revascularizations, 1 unstable angina) occurred during a mean follow-up of 24 months. One noncardiac death occurred. Seventeen events occurred in the group of patients with obstructive CAD and three events occurred in the group of nonobstructive CAD. The event rate was 0% among patients with normal coronary arteries at CTCA. CTCA has a 100% negative predictive value for major cardiac events at 24-month follow-up in patients with normal coronary arteries. |
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Authors:
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Annachiara Aldrovandi; Erica Maffei; Alessandro Palumbo; Sara Seitun; Chiara Martini; Valerio Brambilla; Alessandra Zuccarelli; Giuseppe Tarantini; Annick C Weustink; Nico R Mollet; Livia Ruffini; Girolamo Crisi; Diego Ardissino; Pim J de Feyter; Gabriel P Krestin; Filippo Cademartiri |
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Publication Detail:
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Type: Journal Article Date: 2009-02-18 |
Journal Detail:
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Title: European radiology Volume: 19 ISSN: 1432-1084 ISO Abbreviation: Eur Radiol Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2009-06-05 Completed Date: 2009-08-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 1653-60 Citation Subset: IM |
Affiliation:
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Department of Radiology and Cardiology, Azienda Ospedaliero-Universitaria, Parma, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Coronary Angiography / statistics & numerical data* Coronary Artery Disease / mortality*, radiography* Female Follow-Up Studies Humans Incidence Italy / epidemiology Male Middle Aged Prognosis Reproducibility of Results Sensitivity and Specificity Survival Analysis Survival Rate Tomography, X-Ray Computed / statistics & numerical data* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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