| Prognostic value of cardiac-specific troponins in intracranial hemorrhage. | |
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MedLine Citation:
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PMID: 22864101 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: Cardiac-specific troponin (Tn) serum concentrations have proved to be important diagnostic and prognostic markers for acute myocardial infarction. Elevated levels in the setting of noncardiac diseases such as intracerebral hemorrhage also may provide useful prognostic information regarding outcome. METHODS: A systematic review of the English-language medical literature was performed using PubMed. Articles reporting original data were included. RESULTS: Ten reports qualified for review. A spectrum of cardiac abnormalities was observed in studied patients, sometimes more frequently in those with Tn elevations, whereas some had no such abnormalities, even if Tn was detected. Although some studies suggested a worse outcome in patients with elevated Tn levels, the findings were inconsistent. CONCLUSIONS: At this time, although the literature suggests an association between cardiac-specific Tn elevations and clinical events in patients with intracranial hemorrhage, data are insufficient to conclude that there is a consistent predictive value or to recommend routine Tn monitoring for prognosis. |
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Authors:
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Ashraf S Abdo; Stephen A Geraci |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Southern medical journal Volume: 105 ISSN: 1541-8243 ISO Abbreviation: South. Med. J. Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-08-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0404522 Medline TA: South Med J Country: United States |
Other Details:
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Languages: eng Pagination: 426-30 Citation Subset: AIM; IM |
Affiliation:
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From the Medical Science Department, G.V. (Sonny) Montgomery Veterans Affairs Medical Center, and the Department of Medicine, University of Mississippi School of Medicine, Jackson. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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