Document Detail

Prognostic value of acetylcholine challenge test: a prospective study.
MedLine Citation:
PMID:  6722054     Owner:  NLM     Status:  MEDLINE    
Eleven hundred and nine iron mine workers aged 35 to 55 with normal chest radiographs were submitted to a pulmonary examination consisting of a questionnaire, a clinical examination, and pulmonary function testing including an acetylcholine challenge test. A positive response (decrease of FEV1 of more than 10%) was observed in 210 subjects (Ace+). The remaining 899 had a negative response (Ace-). Bronchitis, asthma, dyspnoea, and obstructive syndrome were more frequent in the Ace+ group. Five years later, 820 subjects were reexamined: occasional cough and sputum and chronic bronchitis appeared more frequently among subjects without symptoms at the first examination but with a positive acetylcholine challenge test. The obstructive syndrome was more often observed and regressed more rarely in the Ace+ group. The results confirm the use of a test of bronchial hyperreactivity as a means of identifying subjects at risk from chronic obstructive lung disease.
Q T Pham; J M Mur; N Chau; M Gabiano; J C Henquel; D Teculescu
Related Documents :
8901444 - A standardized bedside test for assessment of peripheral sympathetic nervous function u...
16403614 - Clinical differences in the global initiative for chronic obstructive lung disease stag...
6859474 - The application of cricoid pressure. an assessment and a survey of its practice.
23250034 - Low utilisation of diagnostic microbiology for community acquired pneumonia in regional...
23483334 - Diagnostic and screening power of neuropsychological testing in detecting mild cognitiv...
21566524 - α4β2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy ha...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  British journal of industrial medicine     Volume:  41     ISSN:  0007-1072     ISO Abbreviation:  Br J Ind Med     Publication Date:  1984 May 
Date Detail:
Created Date:  1984-06-22     Completed Date:  1984-06-22     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370637     Medline TA:  Br J Ind Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  267-71     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acetylcholine / diagnostic use*
Bronchial Provocation Tests*
Lung Diseases, Obstructive / diagnosis
Middle Aged
Occupational Diseases / diagnosis*
Prospective Studies
Respiratory Function Tests
Respiratory Tract Diseases / diagnosis*
Reg. No./Substance:
51-84-3/Acetylcholine; 7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Genotoxic exposure of workers creosoting wood.
Next Document:  Thin layer chromatography of p-aminophenol in urine after mixed exposure to aniline and toluene.