Document Detail

Prognostic table for predicting major cardiac events based on J-ACCESS investigation.
MedLine Citation:
PMID:  19142708     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The event risk of patients with coronary heart disease may be estimated by a large-scale prognostic database in a Japanese population. The aim of this study was to create a heart risk table for predicting the major cardiac event rate. METHODS: Using the J-ACCESS database created by a prognostic investigation involving 117 hospitals and >4,000 patients in Japan, multivariate logistic regression analysis was performed. The major event rate over a 3-year period that included cardiac death, non-fatal myocardial infarction, and severe heart failure requiring hospitalization was predicted by the logistic regression equation. The algorithm for calculating the event rate was simplified for creating tables. RESULTS: Two tables were created to calculate cardiac risk by age, perfusion score category, and ejection fraction with and without the presence of diabetes. A relative risk table comparing age-matched control subjects was also made. When the simplified tables were compared with the results from the original logistic regression analysis, both risk values and relative risks agreed well (P < 0.0001 for both). CONCLUSIONS: The Heart Risk Table was created for patients suspected of having ischemic heart disease and who underwent myocardial perfusion gated single-photon emission computed tomography. The validity of risk assessment using a J-ACCESS database should be validated in a future study.
Kenichi Nakajima; Tsunehiko Nishimura
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-01-08
Journal Detail:
Title:  Annals of nuclear medicine     Volume:  22     ISSN:  0914-7187     ISO Abbreviation:  Ann Nucl Med     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2009-01-14     Completed Date:  2009-02-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8913398     Medline TA:  Ann Nucl Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  891-7     Citation Subset:  IM    
Department of Nuclear Medicine, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, 13-1 Takaramachi, Kanazawa 920-8641, Japan.
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MeSH Terms
Coronary Artery Disease / mortality*,  radionuclide imaging*
Image Interpretation, Computer-Assisted / methods*
Japan / epidemiology
Proportional Hazards Models*
Radiology Information Systems / statistics & numerical data
Reproducibility of Results
Risk Assessment / methods*
Risk Factors
Sensitivity and Specificity
Survival Analysis
Survival Rate
Tomography, Emission-Computed, Single-Photon / statistics & numerical data*
Ventricular Dysfunction, Left / mortality*,  radionuclide imaging*

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