| Prognostic significance of ventricular arrhythmias post-myocardial infarction. | |
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MedLine Citation:
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PMID: 14631474 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Despite improvements in management strategies, ventricular arrhythmias remain important markers of electrical instability and contribute to the identification of patients at increased risk of sudden cardiac death post-myocardial infarction (MI). Over the past 20 years, understanding of pathophysiological mechanisms and implications of various types of ventricular arrhythmias has evolved remarkably. This systematic review details the prognostic significance of ventricular arrhythmias classified by type and time of onset post-MI. Subacute and late premature ventricular complexes are associated with increased mortality independent of left ventricular function. Although nonsustained ventricular tachycardia (VT) in the acute phase post-MI is of questionable significance, later onset heralds poorer prognosis. Sustained monomorphic VT in the acute post-MI phase is associated with infarct extension, heart failure and increased mortality. Extensive wall motion abnormalities, left ventricular dysfunction and aneurysm formation correlate with later postinfarct sustained VT. Inhospital mortality is higher when ventricular fibrillation presents in the acute phase but long term prognosis is not adversely affected. |
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Authors:
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Paul Khairy; Bernard Thibault; Mario Talajic; Marc Dubuc; Denis Roy; Peter G Guerra; Stanley Nattel |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: The Canadian journal of cardiology Volume: 19 ISSN: 0828-282X ISO Abbreviation: Can J Cardiol Publication Date: 2003 Nov |
Date Detail:
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Created Date: 2003-11-21 Completed Date: 2004-01-05 Revised Date: 2008-04-09 |
Medline Journal Info:
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Nlm Unique ID: 8510280 Medline TA: Can J Cardiol Country: Canada |
Other Details:
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Languages: eng Pagination: 1393-404 Citation Subset: IM |
Affiliation:
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Department of Medicine, Montreal Heart Institute, University of Montreal, Montreal, Quebec, Canada. pkhairy@cardio.tch.harvard.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Arrhythmia Agents
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therapeutic use Clinical Trials as Topic Electrocardiography Humans Myocardial Infarction / complications*, drug therapy Predictive Value of Tests Prognosis Risk Factors Survival Analysis Survival Rate Tachycardia, Ventricular / classification*, diagnosis*, drug therapy, etiology |
| Chemical | |
Reg. No./Substance:
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0/Anti-Arrhythmia Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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