| Prognostic significance of right ventricular diastolic function in thalassaemia major. | |
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MedLine Citation:
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PMID: 18224497 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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While left ventricular (LV) restrictive filling pattern is an ominous echocardiographic finding in thalassaemia major (TM), the prognostic significance of right ventricular (RV) diastolic function in patients with TM has not been thoroughly investigated. We studied 45 TM asymptomatic transfusion-dependent patients with normal LV systolic function by Doppler echocardiography. The 15-year cumulative survival rate was 34% in patients with RV restrictive filling pattern (RFP) and 82% in patients with RV non-RFP (log-rank = 10.41, p = 0.0013). Doppler estimation of RV filling pattern is very important in evaluating the prognosis of TM patients and should be performed routinely and using a standardised followup protocol. |
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Authors:
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Georgios K Efthimiadis; Georgios Giannakoulas; Helen P Hassapopoulou; Haralambos I Karvounis; Dimitrios D Tsikaderis; Ioannis H Styliadis; Georgios E Parcharidis |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Swiss medical weekly Volume: 138 ISSN: 1424-7860 ISO Abbreviation: Swiss Med Wkly Publication Date: 2008 Jan |
Date Detail:
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Created Date: 2008-01-28 Completed Date: 2008-04-10 Revised Date: 2011-02-15 |
Medline Journal Info:
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Nlm Unique ID: 100970884 Medline TA: Swiss Med Wkly Country: Switzerland |
Other Details:
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Languages: eng Pagination: 52-4 Citation Subset: IM |
Affiliation:
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First Cardiology Department, AHIPA Hospital, Aristotle University of Thessaloniki, Greece. efthymos@med.auth.gr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Death, Sudden, Cardiac / epidemiology Diastole / physiology* Echocardiography, Doppler Female Heart Ventricles / ultrasonography Humans Male Prognosis Ventricular Dysfunction, Right / mortality, physiopathology* Ventricular Function, Right / physiology* beta-Thalassemia / mortality, physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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