Document Detail


Prognostic significance of pregnancy in stage I melanoma.
MedLine Citation:
PMID:  2802988     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The clinical course of 66 patients with stage I melanoma, diagnosed during pregnancy, treated in the Division of Surgical Oncology at UCLA, was retrospectively reviewed. These patients were compared with 619 nonpregnant female patients with melanoma. There was no significant difference between the pregnant population and control population with respect to location of the primary tumor, age at diagnosis, Clark's level, mean depth of invasion (pregnant females, 1.24 mm vs control, 1.28 mm), and histologic type. The 5-year survival for the women diagnosed with melanoma during pregnancy and for the entire population was 86% and 87%, respectively. These results demonstrate that women diagnosed with melanoma during pregnancy fare no worse than their nonpregnant counterparts. Criteria other than the theoretical effect of pregnancy on the tumor should be used to counsel patients diagnosed with melanoma during pregnancy.
Authors:
J H Wong; E E Sterns; K H Kopald; J A Nizze; D L Morton
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of surgery (Chicago, Ill. : 1960)     Volume:  124     ISSN:  0004-0010     ISO Abbreviation:  Arch Surg     Publication Date:  1989 Oct 
Date Detail:
Created Date:  1989-11-09     Completed Date:  1989-11-09     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9716528     Medline TA:  Arch Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1227-30; discussion 1230-1     Citation Subset:  AIM; IM    
Affiliation:
John Wayne Cancer Clinic, Armand Hammer Laboratories, Jonsson Comprehensive Cancer Center, UCLA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Female
Humans
Male
Melanoma / mortality,  pathology*,  surgery
Neoplasm Invasiveness
Neoplasm Staging
Pregnancy
Pregnancy Complications, Neoplastic / mortality,  pathology*,  surgery
Pregnancy Outcome
Prognosis
Retrospective Studies
Skin Neoplasms / mortality,  pathology*,  surgery
Grant Support
ID/Acronym/Agency:
CA 12582/CA/NCI NIH HHS; CA 29605/CA/NCI NIH HHS; CA 9010/CA/NCI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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