Document Detail


Prognostic significance of normal quantitative planar thallium-201 stress scintigraphy in patients with chest pain.
MedLine Citation:
PMID:  3159779     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The prognostic significance of normal quantitative planar thallium-201 stress scintigraphy was evaluated in patients with a chest pain syndrome. The prevalence of cardiac events during follow-up was related to the pretest (that is, before stress scintigraphy) likelihood of coronary artery disease determined on the basis of symptoms, age, sex and stress electrocardiography. In a consecutive series of 344 patients who had adequate thallium-201 stress scintigrams, 95 had unequivocally normal studies by quantitative analysis. The pretest likelihood of coronary artery disease in the 95 patients had a bimodal distribution. During a mean follow-up period of 22 +/- 3 months, no patient died. Three patients (3%) had a cardiac event: two of these patients (pretest likelihood of coronary artery disease 54 and 94%) had a nonfatal myocardial infarction 8 and 22 months, respectively, after stress scintigraphy, and one patient (pretest likelihood 98%) underwent percutaneous transluminal coronary angioplasty 16 months after stress scintigraphy for persisting anginal complaints. Three patients were lost to follow-up; all three had a low pretest likelihood of coronary artery disease. It is concluded that patients with chest pain and normal findings on quantitative thallium-201 scintigraphy have an excellent prognosis. Cardiac events are rare (infarction rate 1% per year) and occur in patients with a moderate to high pretest likelihood of coronary artery disease.
Authors:
F J Wackers; D J Russo; D Russo; J P Clements
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  6     ISSN:  0735-1097     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  1985 Jul 
Date Detail:
Created Date:  1985-08-07     Completed Date:  1985-08-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  27-30     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angiography
Angioplasty, Balloon
Coronary Disease / complications,  radiography,  therapy
Exercise Test*
Female
Follow-Up Studies
Humans
Male
Middle Aged
Myocardial Infarction / complications
Pain / radionuclide imaging*
Probability
Prognosis
Radioisotopes / diagnostic use*
Thallium / diagnostic use*
Thorax / radionuclide imaging*
Time Factors
Chemical
Reg. No./Substance:
0/Radioisotopes; 7440-28-0/Thallium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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