Document Detail

Prognostic significance of increased thallium-201 lung uptake during dipyridamole myocardial scintigraphy: comparison with exercise scintigraphy.
MedLine Citation:
PMID:  7671178     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare the incidence of cardiac events among patients with increased lung uptake of thallium after dipyridamole stress, matched subjects without such uptake and matched subjects with increased lung uptake during exercise stress. DESIGN: Retrospective case control study based on quantitative and semiquantitative visual consensus analysis of thallium scintigraphy. SETTING: Nuclear cardiology laboratory of a university teaching hospital. PATIENTS: Thirty-six patients with increased lung activity after dipyridamole stress and two groups of matched control subjects identified from 3150 consecutive thallium single photon emission computed tomography studies. INTERVENTIONS: Telephone follow-up and chart reviews to determine the incidence of cardiac events. MAIN RESULTS: Cardiac events were significantly less frequent in the study group with increased lung uptake after dipyridamole stress (two of 36,5%) than in the control group with increased thallium lung uptake at exercise scintigraphy (nine of 36,25%; P = 0.046). CONCLUSIONS: Increased lung uptake of thallium has less ominous short term prognostic significance when observed in association with dipyridamole stress rather than with exercise.
J L Cox; L M Wright; R J Burns
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  11     ISSN:  0828-282X     ISO Abbreviation:  Can J Cardiol     Publication Date:  1995 Sep 
Date Detail:
Created Date:  1995-10-19     Completed Date:  1995-10-19     Revised Date:  2008-04-09    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  689-94     Citation Subset:  IM    
Department of Medicine, Toronto Hospital, Ontario.
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MeSH Terms
Coronary Disease / mortality,  physiopathology*
Dipyridamole / diagnostic use*
Dose-Response Relationship, Radiation
Exercise Test
Lung / radiation effects
Middle Aged
Myocardial Infarction / physiopathology*
Radionuclide Imaging
Thallium Radioisotopes / diagnostic use*,  pharmacology
Vasodilator Agents / diagnostic use*
Reg. No./Substance:
0/Thallium Radioisotopes; 0/Vasodilator Agents; 58-32-2/Dipyridamole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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