| Prognostic significance of glomerular filtration rate estimated by the Japanese equation among patients who underwent complete coronary revascularization. | |
| | |
MedLine Citation:
|
PMID: 21160484 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
An equation that accurately estimates the glomerular filtration rate (GFR) in the Japanese population has been proposed; however, the prognostic significance of estimated GFR (eGFR) defined according to this equation has not been reported. In addition, the prognostic significance of eGFR during long-term follow-up after complete coronary revascularization remains unclear. We assessed the prognostic significance of eGFR values, estimated by the new Japanese equation, in a cohort of patients following complete coronary revascularization. We studied consecutive patients with complete revascularization from 1984 to 1992. Patients on dialysis were excluded. A novel Japanese equation was used to estimate the GFR: eGFR=194 × (serum creatinine)(-1.094) × (age)(-0.287) ( × 0.739 if female). Multivariate Cox proportional hazards regression analyses were performed to determine all-cause and cardiac mortality. We analyzed data of 1809 patients, of whom 571 (31.6%) had an eGFR of 90 ml min(-1) per 1.73 m(2), 917 (50.7%) had an eGFR of 60-89 ml min(-1) per 1.73 m(2), 298 (16.5%) had an eGFR of 30-59 ml min(-1) per 1.73 m(2) and 23 (1.3%) had an eGFR of <30 ml min(-1) per 1.73 m(2). During follow-up (11.4±2.9 years), there were 397 (22.0%) all-cause and 123 (6.8%) cardiac deaths overall. Patients with an eGFR of 30-59 ml min(-1) per 1.73 m(2), and <30 ml min(-1) per 1.73 m(2) revealed significantly greater risk of all-cause mortality than those with eGFR of 90 ml min(-1) per 1.73 m(2) (hazard ratio (HR) 1.91, P<0.001, HR 3.35, P<0.001, respectively). Furthermore, incidence of cardiac death was higher in patients with an eGFR of 30-59 ml min(-1) per 1.73 m(2) than those with an eGFR of 90 ml min(-1) per 1.73 m(2) (HR 2.89, P<0.001). GFR as estimated using the new Japanese equation had a prognostic significance among patients with complete coronary revascularization.Hypertension Research advance online publication, 16 December 2010; doi:10.1038/hr.2010.244. |
| | |
Authors:
|
Takatoshi Kasai; Katsumi Miyauchi; Kan Kajimoto; Naozumi Kubota; Tomotaka Dohi; Ryo Tsuruta; Manabu Ogita; Takayuki Yokoyama; Atsushi Amano; Hiroyuki Daida |
Related Documents
:
|
21429804 - Functional, cosmetic and psychosexual results in adult men who underwent hypospadias co... 21376454 - Assessment of postoperative postvoid residual bladder volume using three-dimensional ul... 21192374 - Hearing results in reconstructing the damaged incus with varying lengths of the modifie... 11426314 - Effect of aesthetic rhinoplasty on respiratory functions. 23579334 - The effects of early aggressive rehabilitation on outcomes after anterior cruciate liga... 17114234 - Cost-effectiveness of the unrestricted use of sirolimus-eluting stents vs. bare metal s... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2010-12-16 |
Journal Detail:
|
Title: Hypertension research : official journal of the Japanese Society of Hypertension Volume: - ISSN: 1348-4214 ISO Abbreviation: - Publication Date: 2010 Dec |
Date Detail:
|
Created Date: 2010-12-16 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9307690 Medline TA: Hypertens Res Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Cardiology, School of Medicine, Juntendo University, Tokyo, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Hypertensive crisis: clinical-epidemiological profile.
Next Document: CASP3 gene single-nucleotide polymorphism (rs72689236) and Kawasaki disease in Taiwanese children.