Document Detail

Prognostic significance of blood pressure measured on rising.
MedLine Citation:
PMID:  11439317     Owner:  NLM     Status:  MEDLINE    
Previous works using ambulatory blood pressure (BP) monitoring demonstrated that independently of the mean level of BP, the variability in BP, or the day-night range, could have prognostic significance. We have also found that the value of BP on rising in the morning is strongly correlated with left ventricular mass of hypertensive individuals independently of the 24-h value. In the present study, we sought its predictive value for cardiovascular complications in a cohort of hypertensive patients. The population studied belongs to a cohort of initially untreated hypertensive patients recruited since 1983 and followed for more than 5 years. Patients were then treated and followed by their family doctor. At entry, all patients were equipped with a device to measure ambulatory BP. They were requested to trigger a measurement manually on rising in the morning (arising BP). The data on their outcome were collected by a physician unaware of the initial state of the patients. A total of 256 patients have been followed up for 5 years or more, 19 were lost to follow-up. The mean follow-up period was 84 +/- 29 months. Cardiovascular complications were recorded in 23 individuals. The arising systolic BP (SBP) was significantly higher in the group who presented a complication. In a stepwise discriminant analysis including age, office, fitting, arising and 24-h average SBPs only age and arising SBP entered the equation. In conclusion, the single BP value measured by an ambulatory device on rising in the morning seems more discriminant of future cardiovascular events than the value of BP measured on fitting the device or the average of three measurements taken under standardised conditions in the hospital or office.
P Gosse; C Cipriano; L Bemurat; D Mas; P Lemétayer; G N'Tela; J Clementy
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of human hypertension     Volume:  15     ISSN:  0950-9240     ISO Abbreviation:  J Hum Hypertens     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-07-05     Completed Date:  2001-08-09     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8811625     Medline TA:  J Hum Hypertens     Country:  England    
Other Details:
Languages:  eng     Pagination:  413-7     Citation Subset:  IM    
Service de Cardiologie-Hypertension artérielle, Hospital Saint André, 1 rue Jean Burguet, 33075 Bordeaux Cedex, France.
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MeSH Terms
Age Factors
Blood Pressure / physiology*
Blood Pressure Monitoring, Ambulatory*
Cardiovascular Diseases / etiology
Chronology as Topic
Cohort Studies
Follow-Up Studies
Hypertension / complications,  diagnosis,  physiopathology
Middle Aged
Predictive Value of Tests
Sex Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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