Document Detail


Prognostic score in liver cirrhosis developed using the Cox's proportional hazard regression model.
MedLine Citation:
PMID:  3589404     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In order to assess the prognostic value of clinical and laboratory variables in liver cirrhosis, 36 of these variables were statistically analyzed in 151 patients followed up for 8 years. The 'survival time' was taken as the reference variable. In a first step we analyzed by log-rank test and by Cox's proportional hazard regression model the data of 98 patients (study group), obtaining 7 prognostically significant variables (age, leukocytes, calcium, potassium, globulins, cholesterol and previous diagnosis). From the regression coefficients of these variables, a risk score was obtained for each patient. To validate the prognostic value of this score, we computed it, using the same coefficients obtained in the study group, in 53 subsequently examined patients (control group) showing that the prognostic score allows the classification of these patients in 3 risk classes with different observed survival times.
Authors:
M Casaril; R Micciolo; G B Gabrielli; G Bellisola; R Corrocher
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  La Ricerca in clinica e in laboratorio     Volume:  17     ISSN:  0390-5748     ISO Abbreviation:  Ric Clin Lab     Publication Date:    1987 Jan-Mar
Date Detail:
Created Date:  1987-07-10     Completed Date:  1987-07-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7613947     Medline TA:  Ric Clin Lab     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  67-76     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Female
Humans
Liver Cirrhosis / diagnosis*
Male
Middle Aged
Prognosis
Regression Analysis
Risk

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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