Document Detail

Prognostic role of myocardial single photon emission computed tomography in the elderly.
MedLine Citation:
PMID:  20033857     Owner:  NLM     Status:  MEDLINE    
The increase in average life expectancy will move the burden of coronary artery disease (CAD) to older patients. Myocardial perfusion imaging by single photon emission computed tomography (SPECT) has been extensively validated for diagnosis and prognostic evaluation in large population series. Yet, its use is usually limited in elderly patients in whom, despite increased absolute cardiovascular risk, diagnostic and therapeutic work-up is often underperformed. American College of Cardiology/American Heart Association guidelines recommend exercise ECG testing as the initial noninvasive method for assessment of CAD in patients with a normal or near-normal resting ECG, regardless of age. However, a considerable proportion of elderly patients is unable to reach an adequate workload during the exercise test and the majority of those undergoing for standard exercise treadmill score are classified as intermediate risk. In elderly patients, SPECT imaging may provide valuable diagnostic and prognostic information for clinical management. In particular, normal or near normal SPECT identifies elderly patients at low risk of major adverse cardiac events at the short-term follow-up.
Pasquale Perrone-Filardi; Pierluigi Costanzo; Santo Dellegrottaglie; Paola Gargiulo; Donatella Ruggiero; Gianluigi Savarese; Antonio Parente; Carmen D'Amore; Alberto Cuocolo; Massimo Chiariello
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology     Volume:  17     ISSN:  1532-6551     ISO Abbreviation:  J Nucl Cardiol     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-22     Completed Date:  2010-10-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9423534     Medline TA:  J Nucl Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  310-5     Citation Subset:  IM    
Department of Clinical Medicine, Cardiovascular and Immunological Sciences, Federico II University, Via S. Pansini 5, Naples, 80131, Italy.
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MeSH Terms
Aged, 80 and over
Cardiology / methods*
Coronary Artery Disease / diagnosis*,  radionuclide imaging*
Exercise Test
Reproducibility of Results
Time Factors
Tomography, Emission-Computed, Single-Photon / methods*
Tomography, X-Ray Computed / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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