Document Detail

Prognostic risk stratification of myocardial ischaemia evaluated by gated myocardial perfusion SPECT in patients with chronic kidney disease.
MedLine Citation:
PMID:  19471925     Owner:  NLM     Status:  In-Process    
PURPOSE: The aim of this study was to identify useful predictors of cardiac events in patients with chronic kidney disease (CKD). METHODS: Among 4,031 patients identified from the Japanese Assessment of Cardiac Events and Survival Study (J-ACCESS) database with suspected or known ischaemic heart disease, we selected 820 with an estimated glomerular filtration rate (eGFR) of < 60 ml/min per 1.73 m(2). RESULTS: A total of 75 cardiac events developed among these 820 patients. The incidence of cardiac events was higher in the group with a lower eGFR. Multivariate Cox analysis indicated that age, diabetes mellitus, end-systolic volume, summed stress score (SSS) and eGFR were predictors of cardiac events. Event rates of patients with SSS >or= 9 were significantly higher in groups with lower eGFR values (< 40 and 40-49 ml/min). CONCLUSION: The SSS value (>or= 9) is a reliable predictor of cardiac events and myocardial single photon emission computed tomography has incremental value for predicting cardiac events and survival in CKD.
Tsuguru Hatta; Shigeyuki Nishimura; Tsunehiko Nishimura
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-05-28
Journal Detail:
Title:  European journal of nuclear medicine and molecular imaging     Volume:  36     ISSN:  1619-7089     ISO Abbreviation:  Eur. J. Nucl. Med. Mol. Imaging     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101140988     Medline TA:  Eur J Nucl Med Mol Imaging     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1835-41     Citation Subset:  IM    
Division of Nephrology, Department of Medicine, Ohmihachiman Community Medical Center, Ohmihachiman-Shi, Shiga 523-0082, Japan.
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