Document Detail

Prognostic parameters in spontaneous intracerebral hematomas with special reference to anticoagulant treatment.
MedLine Citation:
PMID:  2028484     Owner:  NLM     Status:  MEDLINE    
We examined a series of 200 consecutive patients with spontaneous intracerebral hematoma clinically and by computed tomography, excluding patients with trauma, aneurysm, or tumor. Hematoma volume varied from 1 to 230 (average 35) ml, and overall mortality was 30% (60 patients). Of the 200 patients, 14% (28) were receiving anticoagulants; among these 28 patients hematoma volume averaged 72 ml and mortality 57% (16 patients). The 140 survivors were followed for 2-24 months. Our findings indicate that anticoagulation therapy after previous cerebral infarction or embolism of cardiogenic origin did not predispose to intracerebral hemorrhage. Prognosis was poor when the initial level of consciousness was low and the hematoma volume exceeded 50 ml in combination with dilatation of the contralateral ventricle. An intracerebral hematoma of greater than 80 ml volume was always fatal, regardless of therapy. With volumes of 40-80 ml, early surgical evacuation of the lobar hematoma may improve outcome.
J A Rådberg; J E Olsson; C T Rådberg
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  22     ISSN:  0039-2499     ISO Abbreviation:  Stroke     Publication Date:  1991 May 
Date Detail:
Created Date:  1991-06-10     Completed Date:  1991-06-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  571-6     Citation Subset:  IM    
Department of Neurology, University Hospital, Linköping, Sweden.
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MeSH Terms
Aged, 80 and over
Cerebral Hemorrhage / diagnosis*,  drug therapy,  physiopathology
Hematoma / diagnosis*,  drug therapy,  physiopathology
Middle Aged
Tomography, X-Ray Computed
Warfarin / therapeutic use
Reg. No./Substance:

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