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Prognostic importance of electrocardiographic abnormalities in patients with acute noncardiac conditions.
MedLine Citation:
PMID:  22825535     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The electrocardiogram's (ECG) ability to aid in the diagnosis and risk stratification of patients with acute coronary syndromes is well established. We sought to investigate the prognostic significance of ECG abnormalities in patients with noncardiac conditions in the emergency department. Patients presenting to the emergency department who were evaluated for possible acute coronary syndrome were consecutively enrolled and an initial ECG was obtained (n = 1024). Only patients with noncardiac diagnoses were reviewed in this analysis (n=493) and 30-month follow-up was obtained. Sinus tachycardia, atrial fibrillation/flutter, ST depression, and left bundle branch block were associated with increased 30-month mortality. After controlling for history of coronary artery disease, age, sex, diabetes mellitus, hypertension, and renal insufficiency, sinus tachycardia and ST-segment depression ≥1 mm were independent predictors of 30-month mortality with a hazard ratio of 2.33 (95% confidence interval, 1.36-4.00; P = 0.002) and 2.49 (95% confidence interval, 1.10-5.67; P = 0.029), respectively. In conclusion, ST-segment depression and sinus tachycardia in patients presenting to the hospital with noncardiac conditions are independently associated with increased 30-month mortality.
Authors:
Carlos Calle-Muller; David Nori; Richard Nowak; Michael Hudson; Gordon Jacobsen; James McCord
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Critical pathways in cardiology     Volume:  11     ISSN:  1535-2811     ISO Abbreviation:  Crit Pathw Cardiol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-07-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101165286     Medline TA:  Crit Pathw Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  147-51     Citation Subset:  IM    
Affiliation:
From the *Department of Internal Medicine, Henry Ford Hospital, Detroit, MI; †Department of Cardiology, Beaumont Hospital, Royal Oak, MI; ‡Department of Emergency Medicine, Henry Ford Hospital, Detroit, MI; ‡Henry Ford Heart and Vascular Institute, Detroit, MI; and ¶Department of Public Health Sciences, Henry Ford Hospital, Detroit, MI.
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