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Prognostic factors for treatment outcomes in transient tachypnea of the newborn.
MedLine Citation:
PMID:  22747488     Owner:  NLM     Status:  Publisher    
Background:  Transient tachypnea of the newborn (TTN) is a clinical syndrome associated with respiratory distress usually seen shortly after delivery in infants. This study aims to determine the risk factors predicting treatment outcomes in infants with TTN. Methods:  Data from 236 infants diagnosed with TTN during the study period were evaluated retrospectively. Logistic regression analyses were performed to select significant risk factor for prognosis (prolonged oxygen therapy, apply of mechanical ventilator, and prolonged hospital stay) of TTN among components of clinical variables. Results:  Of the 236 TTN infants, 111 (47.0%) infants were delivered by cesarean section (C/S) without labor, 29 (12.3%) infants were delivered by C/S with labor, and 96 (40.7%) were delivered by vaginal birth. Lower Apgar score at 1 min (odds ratio [OR]: 3.03, 95% confidence interval [CI]: 1.25-7.36) and lower umbilical artery pH (OR: 4.00, 95% CI 1.55-10.49) were associated with a significantly increased risk for mechanical ventilator care. Also, late-preterm (OR: 4.70, 95% CI: 2.11-10.49) was independently associated with risk of prolonged duration of hospital stay. Conclusions:  Late-preterm, lower initial umbilical artery pH (<7.25), and lower Apgar score at 1 min were independently associated with poor prognostic treatment outcomes in infants with TTN. © 2012 The Authors. Pediatrics International © 2012 Japan Pediatric Society.
Seon-Yeong Bak; Youn-Ho Shin; Ji-Hyun Jeon; Kyu-Hee Park; Jin-Hee Kang; Dong-Hyun Cha; Man-Yong Han; Heui-Seung Jo; Kyu-Hyung Lee; Cho-Ae Lee
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-1
Journal Detail:
Title:  Pediatrics international : official journal of the Japan Pediatric Society     Volume:  -     ISSN:  1442-200X     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100886002     Medline TA:  Pediatr Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Authors. Pediatrics International © 2012 Japan Pediatric Society.
Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Korea; Department of Pediatrics, CHA Kangnam Medical Center, CHA University, Korea; Department of Obstetrics and Gynecology, CHA Kangnam Medical Center, CHA University, Korea.
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