| Prognostic factors for successful outcome in patients undergoing controlled ovarian stimulation and intrauterine insemination. | |
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MedLine Citation:
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PMID: 14530528 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the prognostic factors associated with successful outcome following controlled ovarian stimulation and intrauterine insemination. DESIGN: Retrospective analysis. SETTING: University-based assisted reproductive technology centre, Hong Kong. PATIENTS AND METHODS: Patients included 292 couples undergoing 600 treatment cycles, following a standard protocol of human menopausal gonadotrophin injections. Multiple logistic regression analysis was performed to determine which demographic and sperm parameters gave the maximum discrimination to predict pregnancy. RESULTS: One hundred and eleven pregnancies resulted from treatment. The pregnancy rates were 18.5% per cycle and 37.9% per couple. The age of the women was significantly lower for pregnant cycles, and the serum oestradiol levels and number of follicles greater than 16 mm in diameter were significantly higher, compared with non-pregnant cycles. The sperm concentration and number of motile spermatozoa were also significantly increased in pregnant cycles. Pregnancy rate was significantly increased when the raw semen sample contained 20 million/mL or more spermatozoa, normal forms comprised 7% or more, and when the number of motile spermatozoa in inseminated samples was 1 million or greater. CONCLUSION: Using multiple logistic regression analysis, age of the women and serum oestradiol level had the maximum power to predict pregnancy following ovarian stimulation and intrauterine insemination. |
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Authors:
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G Makkar; E H Y Ng; W S B Yeung; P C Ho |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine Volume: 9 ISSN: 1024-2708 ISO Abbreviation: Hong Kong Med J Publication Date: 2003 Oct |
Date Detail:
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Created Date: 2003-10-07 Completed Date: 2004-06-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9512509 Medline TA: Hong Kong Med J Country: China |
Other Details:
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Languages: eng Pagination: 341-5 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, ROC. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Estradiol / blood Female Humans Insemination, Artificial, Homologous* Logistic Models Male Maternal Age Outcome Assessment (Health Care) Ovarian Follicle Ovulation Induction* Pregnancy Pregnancy Rate Prognosis Retrospective Studies Sperm Count Sperm Motility Spermatozoa |
| Chemical | |
Reg. No./Substance:
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50-28-2/Estradiol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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