Document Detail

Prognostic factors in the treatment of generalized aggressive periodontitis: II. Effects of smoking on initial outcome.
MedLine Citation:
PMID:  16856898     Owner:  NLM     Status:  MEDLINE    
AIMS: The aim of this study was to investigate the effects of smoking on the response to non-surgical treatment for aggressive periodontitis. METHODS: Seventy-nine patients with generalized aggressive periodontitis were included in the study; 20 were smokers. All patients received a course of non-surgical periodontal therapy and outcomes assessed 10 weeks post-operatively. Non-responding patients were designated if they had 30% or more non-responding deep sites. RESULTS: At baseline, bleeding scores were lower in smokers. There was no difference in baseline plaque, pocket depth (PD), recession or clinical attachment levels (CALs); when sites were selected by equal levels of CAL, increased recession was seen in smokers. Outcomes were poorer in smokers (mean PD change 1.75+/-0.56 versus 2.23+/-0.87 mm). The odds ratio for 30% of sites not responding in smokers was 2.9; for 40% non-responding it was 5.9. Smoking altered the distribution of site-specific responses to increase specifically the number of non-responding sites. There was no significant difference in responses between ex-smokers and never-smokers. CONCLUSIONS: The results demonstrate that smoking is a major risk factor for poor response to initial treatment and emphasize the importance of smoking cessation in periodontal therapy.
Francis J Hughes; Mahnaz Syed; Bindhu Koshy; Nagihan Bostanci; Ian J McKay; Michael A Curtis; Wagner Marcenes; Raymond E Croucher
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-07-20
Journal Detail:
Title:  Journal of clinical periodontology     Volume:  33     ISSN:  0303-6979     ISO Abbreviation:  J. Clin. Periodontol.     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-08-21     Completed Date:  2006-10-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0425123     Medline TA:  J Clin Periodontol     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  671-6     Citation Subset:  D; IM    
Collaborative Group in Risk Factors for Periodontal Disease, Centre for Adult Oral Health, Institute of Dentistry, London, UK.
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MeSH Terms
Cohort Studies
Dental Plaque / therapy
Follow-Up Studies
Gingival Hemorrhage / therapy
Gingival Recession / therapy
Periodontal Attachment Loss / therapy
Periodontal Pocket / therapy
Periodontitis / therapy*
Smoking / adverse effects,  physiopathology*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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