| Prognostic factors in the treatment of generalized aggressive periodontitis: I. Clinical features and initial outcome. | |
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MedLine Citation:
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PMID: 16856897 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: The aims of this study were to investigate prognostic factors for initial response to non-surgical periodontal treatment for generalized aggressive periodontitis. METHODS: Seventy-nine patients with generalized aggressive periodontitis were included in this prospective follow-up intervention study. Patients' clinical and demographic parameters were collected at baseline and 10 weeks following a standard course of treatment (four visits of non-surgical root surface debridement together with OHI as required). The relationship between clinical variables and treatment outcome were analysed at site-specific level by chi(2) analysis and for patient-specific variables by logistic regression. RESULTS: In general, there was a good response to the treatment provided. In deep sites the mean pocket depth reduction was 2.11+/-2.01 mm. Site-specific analysis showed that the presence of plaque had a small but significant predictive effect on outcome (odds ratio 1.4). Sites on teeth with grade II/III mobility showed a significantly reduced response to treatment. Twenty-five patients were classified as "non-responders". Current smoking was strongly associated with non-responding patients (odds ratio 3.8) in a logistic regression model; plaque, baseline bleeding and initial pocket depth were not significantly associated with treatment outcomes. CONCLUSIONS: Overall, the results emphasize the importance of smoking as a negative prognostic factor, and suggest that treatment outcomes may be determined by a wide range of different determinants requiring further study. |
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Authors:
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Francis J Hughes; Mahnaz Syed; Bindhu Koshy; Valeria Marinho; Nagihan Bostanci; Ian J McKay; Michael A Curtis; Raymond E Croucher; Wagner Marcenes |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2006-07-20 |
Journal Detail:
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Title: Journal of clinical periodontology Volume: 33 ISSN: 0303-6979 ISO Abbreviation: J. Clin. Periodontol. Publication Date: 2006 Sep |
Date Detail:
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Created Date: 2006-08-21 Completed Date: 2006-10-27 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0425123 Medline TA: J Clin Periodontol Country: Denmark |
Other Details:
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Languages: eng Pagination: 663-70 Citation Subset: D; IM |
Affiliation:
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Collaborative Group in Risk Factors for Periodontal Disease, Institute of Dentistry, Queen Mary's School of Medicine, London, UK. f.j.hughes@qmul.ac.uk |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cohort Studies Dental Plaque / therapy Dental Scaling Female Follow-Up Studies Furcation Defects / therapy Gingival Hemorrhage / therapy Humans Longitudinal Studies Male Oral Hygiene Periodontal Attachment Loss / therapy Periodontal Pocket / therapy Periodontitis / therapy* Prognosis Prospective Studies Root Planing Smoking / adverse effects Subgingival Curettage Tooth Mobility / therapy Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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