| Prognostic factors in the surgical treatment of patients with oral carcinoma. | |
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MedLine Citation:
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PMID: 19183373 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of the study was to analyse the clinical outcome of patients treated surgically for oral carcinoma. A retrospective cohort study was undertaken of 356 patients with oral cavity cancer whose clinicopathological information had been collected prospectively onto a dedicated head and neck database. Disease recurrence and survival were assessed. Neck metastases occurred in 42% of patients. Tumour thickness (both 2 and 5 mm) predicted the presence of nodal metastases. Both pathological T stage (P < 0.001) and tumour thickness cut-off of 5 mm (P = 0.03) were independent predictors of disease-specific survival. With a median follow up of 41 months, overall survival at 5 years was 59% and disease-specific survival was 73%. Patients with thick tumours have a high risk of nodal metastases and this supports the liberal use of elective selective neck dissection in patients with clinically negative necks. |
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Authors:
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Rajan S Patel; Jonathan R Clark; Richard Dirven; Rebecca Wyten; Kan Gao; Christopher J O'Brien |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: ANZ journal of surgery Volume: 79 ISSN: 1445-2197 ISO Abbreviation: ANZ J Surg Publication Date: 2009 Jan-Feb |
Date Detail:
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Created Date: 2009-02-02 Completed Date: 2009-05-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101086634 Medline TA: ANZ J Surg Country: Australia |
Other Details:
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Languages: eng Pagination: 19-22 Citation Subset: IM |
Affiliation:
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Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, University of Sydney, Sydney, New South Wales, Australia. drrajanspatel@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Carcinoma, Squamous Cell / mortality, pathology, surgery* Female Head and Neck Neoplasms / mortality, pathology, surgery* Humans Lymph Node Excision Male Middle Aged Mouth Neoplasms / surgery Neoplasm Staging Prognosis Retrospective Studies Survival Analysis Tongue Neoplasms / surgery |
| Comments/Corrections | |
Comment In:
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ANZ J Surg. 2009 Jan-Feb;79(1-2):7-8
[PMID:
19183369
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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