| Prognostic assessment of end-stage cardiac failure. | |
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MedLine Citation:
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PMID: 9684036 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Heart failure is not a disease, but rather a complex clinical syndrome that is growing in incidence and carries a very high morbidity and mortality. Although the incidence in the general adult population in the Western world is between 1% and 2%, the frequency increases rapidly in the elderly affecting more than 10% of the individuals over the age of 75 years. The treatment of patients with end-stage chronic heart failure (CHF) is difficult. The two major goals in the treatment of heart failure are to increase the duration (slow its progression) and quality of life (relief of symptoms). Understanding the severity of the syndrome of heart failure in terms of its prognosis can be particularly important in planning long-term management and in counselling the patient. The introduction of aggressive interventional therapies such as active haemodynamic support with ventricular assist devices, or heart transplantation emphasizes the importance of quantitating the risk of death in order to properly select patients for these more aggressive treatments. In large-scale trials it has been possible to identify markers that serve as significant predictors of mortality. Of these, the detection and quantification of neurohumoral activation have gained the most recent attention. Here, we discuss some of the prognostic tools in current use for heart failure patients and their applicability to patients with advanced heart failure. |
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Authors:
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P Vranckx; J Van Cleemput |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Acta cardiologica Volume: 53 ISSN: 0001-5385 ISO Abbreviation: Acta Cardiol Publication Date: 1998 |
Date Detail:
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Created Date: 1998-10-28 Completed Date: 1998-10-28 Revised Date: 2009-06-11 |
Medline Journal Info:
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Nlm Unique ID: 0370570 Medline TA: Acta Cardiol Country: BELGIUM |
Other Details:
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Languages: eng Pagination: 121-5 Citation Subset: IM |
Affiliation:
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Department of Cardiology, University Hospital Gasthuisberg, University of Leuven, Belgium. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Female Heart Failure / diagnosis*, mortality, therapy Heart-Assist Devices Humans Male Prognosis Quality of Life Survival Rate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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