| Prognostic Implications of Creatine Kinase-MB Elevation After Percutaneous Coronary Intervention: Results From the Evaluation of Drug-Eluting Stents and Ischemic Events (EVENT) Registry. | |
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MedLine Citation:
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PMID: 21972402 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: <0.001). Spline analysis using peak CK-MB as a continuous variable suggested a graded, nonlinear relationship with 1-year mortality, with an inflection point at ≈30 ng/mL.Conclusions-Among unselected patients undergoing PCI, there is a graded relationship between CK-MB elevation after PCI and 1-year mortality that is particularly strong for large CK-MB elevations (>30 to 50 ng/mL). Future studies that include pMI as a clinical end point should consider using a core laboratory to assess CK-MB (to ensure consistency) and raising the threshold for defining pMI above current levels (to enhance clinical relevance). |
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Authors:
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Jason B Lindsey; Kevin F Kennedy; Joshua M Stolker; Ian C Gilchrist; Debabrata Mukherjee; Steven P Marso; Michael J Pencina; Neal S Kleiman; David J Cohen |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-4 |
Journal Detail:
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Title: Circulation. Cardiovascular interventions Volume: - ISSN: 1941-7632 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-5 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101499602 Medline TA: Circ Cardiovasc Interv Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City, Kansas City, MO. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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