| Prognosis of post-neonatal respiratory distress syndrome (RDS) treated with positive end-expiratory pressure ventilation (PEEP). | |
| | |
MedLine Citation:
|
PMID: 1105779 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Thirty-six patients with respiratory distress syndrome (RDS) were treated with mechanical ventilation with positive end-expiratory pressure (PEEP). In 16 patients the RDS was the result of direct pulmonary injury due to chest trauma (group A), and in 20 patients the RDS followed non-direct injury of the lungs (group B). Fifteen patients died. At the moment of death the RDS had disappeared. No difference in mortality existed between groups A and B. Four patients died from causes unrelated to the RDS, one patient died from an avoidable error in the treatment. The ultimate outcome did not seem to be related to age, use of mechanical ventilation or PEEP, or occurrence of complications (e.g. a pneumothorax, which appeared to be related rather to the chest trauma). Of probably prognostic significance was the presence of a combination of massive aspiration and RDS. Of the 12 patients who suffered from this combination, nine died. PEEP ventilation was more unsuccessful in raising PaO2 appreciably in these patients than in others. The combination of massive aspiration and RDS posses a therapeutic dilemma. PEEP ventilation is invaluable in the treatment of RDS. Interruption of the PEEP within the first 1-2 days may sometimes result in massive recurrence of the RDS. Endotracheal suctioning which is a prerequisite for the treatment of massive aspiration, may under these circumstances be virtually impossible within this period. A compromise, including PEEP ventilation for as short a period as possible (usually no longer than 2 to 3 days) without interruption, followed thereafter by intensive physiotherapy with endotracheal suctioning, may succeed in saving some of the patients. |
| | |
Authors:
|
J R van Haeringen; E J Blokzijl; W van Dijl; J W Kleine; R Peset; H J Sluiter |
Related Documents
:
|
3389889 - Severe hypoxaemia in pertussis. 17646499 - Continuous oximetry/capnometry monitoring reveals frequent desaturation and bradypnea d... 10764299 - Physiologic determinants of ventilator dependence in long-term mechanically ventilated ... 7005549 - Selective use of ventilator therapy in flail chest injury. 588389 - Oxygen therapy after thoracotomy. 3800139 - Airway occlusion pressure. an important indicator for successful weaning in patients wi... 8264869 - Alpha-melanocyte-stimulating hormone is present in the inferior petrosal sinuses in pat... 14746789 - Conscious sedation for endoscopic and non-endoscopic interventional gastrointestinal pr... 8457789 - Recombinant human erythropoietin and the anemia of multiple myeloma. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Scandinavian journal of respiratory diseases Volume: 56 ISSN: 0036-5572 ISO Abbreviation: Scand J Respir Dis Publication Date: 1975 |
Date Detail:
|
Created Date: 1976-02-27 Completed Date: 1976-02-27 Revised Date: 2009-11-11 |
Medline Journal Info:
|
Nlm Unique ID: 0055427 Medline TA: Scand J Respir Dis Country: DENMARK |
Other Details:
|
Languages: eng Pagination: 185-94 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Child Child, Preschool Female Humans Lung Injury Male Middle Aged Oxygen / blood Partial Pressure Pneumonia, Aspiration / complications Pneumothorax / complications Positive-Pressure Respiration* Prognosis Respiratory Insufficiency / complications, mortality, therapy* |
| Chemical | |
Reg. No./Substance:
|
7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The value of roentgen irradiation in the treatment of painful degenerative and inflammatory musculos...
Next Document: Function and homeostasis of copper and zinc in mammals.