Document Detail

Prognosis of patients with good exercise capacity and mildly abnormal exercise echocardiography results: identification of an at-risk subgroup.
MedLine Citation:
PMID:  15947766     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Patients with good exercise capacity and mildly abnormal exercise echocardiography results have a favorable overall prognosis. OBJECTIVE: We sought to define subgroups that might be at higher risk. METHODS: We examined outcomes of 868 patients (women, > or = 5 metabolic equivalents; men, > or = 7 metabolic equivalents) with mild rest- or exercise-induced wall-motion abnormalities and evaluated potential predictors of time to cardiac death or nonfatal myocardial infarction (MI). RESULTS: Mean age was 64 +/- 10 years; 477 patients (55%) were men. Mean follow-up was 3.1 +/- 1.5 years; cardiac event rate was 1.2% per person-year. A history of MI was the only significant predictor (risk ratio, 3.9; 95% confidence interval, 1.9-7.8; P = .0001), with 1-, 3-, and 5-year event-free survival of 98.5% +/- 1.1%, 92.6% +/- 2.6%, and 83.3% +/- 5.1%, respectively (event rate, 3.4%). CONCLUSIONS: Patients with a history of MI have a higher annual cardiac event rate and may benefit from reevaluation, whereas no history of MI connotes a favorable prognosis.
Robert B McCully; Steve R Ommen; Kyle W Klarich; Kelli N Burger; Douglas W Mahoney; Patricia A Pellikka
Related Documents :
21747296 - Time course of endothelial adaptation after acute and chronic exercise in patients with...
9817476 - Effect of percutaneous transluminal coronary angioplasty on exercise in patients with a...
21896936 - Exercise training alters the balance between vasoactive compounds in skeletal muscle of...
21614506 - Chronic camkii inhibition blunts the cardiac contractile response to exercise training.
17409306 - Progressive exercise for anabolism in kidney disease (peak): a randomized, controlled t...
9505236 - Recommended daily exercise for japanese does not increase the protein requirement in se...
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  18     ISSN:  1097-6795     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-06-10     Completed Date:  2006-04-11     Revised Date:  2007-11-02    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  644-8     Citation Subset:  IM    
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Disease-Free Survival
Echocardiography / statistics & numerical data*
Exercise Test / statistics & numerical data*
Exercise Tolerance*
Minnesota / epidemiology
Myocardial Infarction / mortality*,  ultrasonography*
Reproducibility of Results
Risk Assessment / methods*
Risk Factors
Sensitivity and Specificity
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Ultrasonic tissue characterization predicts left ventricular remodeling in patients with acute anter...
Next Document:  Incidence of cerebral embolism after cardioversion of atrial fibrillation: a prospective study with ...