| Prognosis and outcome of neonates treated either with veno-arterial (VA) or veno-venous (VV) ECMO. | |
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MedLine Citation:
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PMID: 8647585 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A comparison was done between neonates requiring veno-arterial (VA) ECMO (too small jugular vein, inability to insert a 12 Fr double lumen catheter or cardio-circulatory instability) and neonates treated with veno-venous (VV) ECMO in the same period of time. From 1991-1995 ECMO was done in 48 neonates after failure of maximum conventional treatments, NO-inhalation and HFOV. 30/48 babies were treated with VV-ECMO, with a switch to VA-ECMO later on in 3 of them. In 18 infants VA-ECMO was installed primarily. Differences between the VA- and VV-ECMO group were: the OI was higher in the VV-treated babies (62 +/- 20 vs. 48 +/- 13, p < 0.03), as were birth weight (3385 +/- 570 vs. 2963 +/- 653 g, p < 0.04), gestational age (39.7 +/- 1.6 vs. 37.9 +/- 2.7 weeks, p < 0.01) and MAP (18.7 +/- 2.2 vs. 17.1 +/- 2.4 cm H2O, p < 0.05). Severe ICH's occurred more frequently in the VA-treated babies (29 vs. 7%, p < 0.05), the rate of other complications was equal. The mortality rates were 43% (VA) and 15% (VV), p < 0.05. About one third of neonatal ECMO candidates will be treated with VA-ECMO, even if the VV-ECMO technique is available. Need for VA-ECMO implies--due to a higher number of preterm babies and a greater severity of illness before ECMO--a higher incidence of ICH's and a higher mortality rate. |
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Authors:
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V Varnholt; P Lasch; J Sartoris; W Koelfen; W Kachel; C Lorenz; H Wirth |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: The International journal of artificial organs Volume: 18 ISSN: 0391-3988 ISO Abbreviation: Int J Artif Organs Publication Date: 1995 Oct |
Date Detail:
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Created Date: 1996-07-19 Completed Date: 1996-07-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7802649 Medline TA: Int J Artif Organs Country: ITALY |
Other Details:
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Languages: eng Pagination: 569-73 Citation Subset: IM |
Affiliation:
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Kinderklinik, Universitäts-Klinikun, Mannheim, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Birth Weight Blood Pressure Extracorporeal Membrane Oxygenation* Female Gestational Age Humans Hypertension, Pulmonary / complications, mortality, therapy* Infant, Newborn Longitudinal Studies Male Oxygen Consumption Prognosis Respiration, Artificial Respiratory Insufficiency / etiology, mortality, therapy* Survival Rate Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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