Document Detail

Prognosis and long-term results of surgically treated aortic stenosis.
MedLine Citation:
PMID:  2969807     Owner:  NLM     Status:  MEDLINE    
A total of 675 patients (mean age 60 +/- 11 years, range 22-85, 71% males) with calcified pure aortic stenosis (490) or mixed lesions (185) had an aortic prosthesis: 290 Starr-Edwards, 147 Bjork, 18 other mechanical valves, 163 pericardial xenografts, 57 porcine xenografts; 76 patients simultaneously underwent a coronary bypass, 12 a replacement of ascending aorta, and six a mitral valvuloplasty. Preoperatively, 67% were in functional class III or IV (NYHA); 69.5% had a coronary arteriography: significant coronary stenosis was observed in 27% of patients. The operative mortality was 6.8% depending on the functional class at surgery, age (4.9% before 70 years, vs. 12.5% after), and the date of surgery (8.1% before 1983 vs. 3.7% after). The 10- and 15-year actuarial survival rates were 62 +/- 3% and 44 +/- 4%, respectively. No significant differences were observed between patients with pure aortic stenosis and mixed aortic lesions. In patients over 70 years, the survival rates were 71 +/- 5% at five years and 51 +/- 10% at 10 years. Age, functional class, degree of congestive heart failure, and degree of cardiomegaly were the main preoperative predictors of late death. At 10 years, 88% of patients were free from myocardial dysfunction, 87% from thromboembolic events, and 89% from haemorrhages. We conclude that in this type of valvulopathy, short- and long-term surgical results are good despite the fact that most patients are elderly and in an advanced functional class.
B Cormier; P Luxereau; C Bloch; P Ducimetiere; F Boustani; G Badaoui; P Dybantsa; P Cheung; G Preud'homme; J Acar
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European heart journal     Volume:  9 Suppl E     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-09-21     Completed Date:  1988-09-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  113-20     Citation Subset:  IM    
Department of Cardiology, Hôpital Tenon, Paris, France.
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MeSH Terms
Age Factors
Aged, 80 and over
Aortic Valve
Aortic Valve Stenosis / etiology,  surgery*
Calcinosis / surgery
Heart Valve Prosthesis / adverse effects,  mortality*
Middle Aged
Polyethylene Terephthalates
Reg. No./Substance:
0/Polyethylene Terephthalates

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