| Prognosis in patients with low left ventricular ejection fraction after myocardial infarction. Importance of exercise capacity. | |
| | |
MedLine Citation:
|
PMID: 2598426 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The measurement of left ventricular ejection fraction (LVEF) plays a key role in many strategies for managing patients after acute myocardial infarction. We tested the hypothesis that exercise capacity 1 month after myocardial infarction provides additional information in patients with a low LVEF and therefore assists in risk stratification. One hundred fifteen patients, with documented myocardial infarction and LVEF less than 35% by gated radionuclide scan 1 month after acute myocardial infarction, were followed up for 2 months to 7 years. Exercise capacity was estimated from a treadmill test 1 month after infarction. Using the Cox proportional hazards model, exercise capacity was a significant predictor of death or reinfarction. The relative risk of death, based on a comparison between the lowermost quintile (less than 4 METS) and uppermost quintile (greater than 7 METS), was 3.5 (95% confidence interval, 1.1-9.7); the relative risk in the fourth, third, and second quintile was 2.7, 2.1, and 1.6, respectively. In a multivariate analysis, the observed effect of a good exercise capacity was independent of LVEF. These data indicate that in patients with a low LVEF after myocardial infarction, useful prognostic information can be obtained from exercise testing. |
| | |
Authors:
|
L Pilote; J Silberberg; R Lisbona; A Sniderman |
Related Documents
:
|
18651416 - Prognostic significance of submaximal negative dobutamine stress echocardiography: a 3-... 11975766 - The intermediate ccu admission: a preliminary study. 18494386 - Risk stratification. 9648086 - Diagnostic accuracy and prognostic value of combined dipyridamole-exercise thallium ima... 10310856 - Pacemakers and prospective payment. 20536456 - Thymosin beta4: a key factor for protective effects of eepcs in acute and chronic ische... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Circulation Volume: 80 ISSN: 0009-7322 ISO Abbreviation: Circulation Publication Date: 1989 Dec |
Date Detail:
|
Created Date: 1990-02-01 Completed Date: 1990-02-01 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0147763 Medline TA: Circulation Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1636-41 Citation Subset: AIM; IM |
Affiliation:
|
Division of Cardiology, Royal Victoria Hospital, Montreal, Quebec, Canada. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Exercise
/
physiology* Exercise Test Female Follow-Up Studies Humans Male Middle Aged Myocardial Infarction / mortality*, physiopathology Prognosis Proportional Hazards Models Risk Factors Stroke Volume / physiology* Survival Rate Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Four-year follow-up study in patients with angina pectoris and normal coronary arteriograms ("syndro...
Next Document: Selective enhancement of the cardiac sympathetic response to exercise by anginal chest pain in human...