Document Detail


Prognosis in medically-treated coronary artery disease: influence of ejection fraction compared to other parameters.
MedLine Citation:
PMID:  1157237     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The prognostic value of the left ventricular ejection fraction(EF) was compared to that of other commonly used indices--severity of coronary artery disease, left ventricular end-diastolic pressure, cardiac index, and abnormal ECG--in 144 patients with coronary artery disease followed for an average of 14 months on medical management. During this period, 14 patients (10%) died. Analysis of the mortality demonstrated that the EF was the most powerful predictor of short-term survival. Thus, patients with three-vessel coronary artery disease and anormal EF (greater than 0.50) had a significantly lower mortality (12%) than did patients with three-vessel CAD and a reduced EF (33%, P less than 0.001). Similar comparisons were observed within the subgroups with abnormal hemodynamics or an abnormal ECG. Therefore, the EF appears to be an important prognostic guide in the medical therapy of coronary artery disease, and is of significantly more discriminant value than other measurements when combined abnormalities exist.
Authors:
G R Nelson; P F Cohn; R Gorlin
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Circulation     Volume:  52     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1975 Sep 
Date Detail:
Created Date:  1975-11-20     Completed Date:  1975-11-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  408-12     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Boston
Cardiac Output
Coronary Disease / drug therapy,  mortality,  physiopathology*
Follow-Up Studies
Humans
Middle Aged
Prognosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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