Document Detail

Prognosis of dilated cardiomyopathy: from a retrospective to a prospective study employing multivariate analysis.
MedLine Citation:
PMID:  3669277     Owner:  NLM     Status:  MEDLINE    
To determine the prognostic factors of dilated cardiomyopathy (DCM), a retrospective long-term investigation of 111 patients seen between 1967 and 1983 was carried out. Fifty-four deaths were divided into 3 subgroups: (1): sudden death (n = 6); (2): sudden death on the basis of heart failure (n = 17); (3): refractory heart failure death (n = 31). Multivariate analysis was employed to ascertain the prognostic score, which was constructed from the grading of the New York Heart Association functional classification, the cardiothoracic ratio, electrocardiographic findings and cardiac function. Individual variables were indicated on the first (I) and second (II) principal component axes. The mean center points for the death modes were as follows: (1): I = -0.4, II = +0.8, (2): I = +0.7, II = +1.1, (3): I = +1.4, II = -0.8. Surviving cases (n = 57) showed I = -0.6, II = +0.1. Forty-one cases examined during 1984-1985 were analyzed to evaluate the prognostic efficacy of this score. Fourteen of 17 cases (82%) located in the refractory heart failure death group died within one year after determination of the prognosis, showing thereby that the prognostic determination by multivariate analysis is effective.
S Ogasawara; M Sekiguchi; M Hiroe; T Komazawa; Y Kawai; N Fujita; K Nakamura; H Kasanuki; E Tanaka; K Kobayashi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Japanese circulation journal     Volume:  51     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1987 Jun 
Date Detail:
Created Date:  1987-11-27     Completed Date:  1987-11-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  699-706     Citation Subset:  IM    
Heart Institute of Japan, Tokyo Women's Medical College.
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MeSH Terms
Cardiomyopathy, Dilated / diagnosis,  mortality*
Death, Sudden / epidemiology
Follow-Up Studies
Heart Catheterization
Heart Failure / diagnosis,  mortality
Middle Aged
Myocardium / pathology
Prospective Studies
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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