| Prognosis of different types of atrial fibrillation in the primary angioplasty era. | |
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MedLine Citation:
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PMID: 22990415 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Atrial fibrillation (AF) has been associated with a poor prognosis in patients with ST-segment elevation myocardial infarction. There is considerable controversy regarding the prognostic implications of different types of AF. METHODS AND RESULTS: We analyzed 913 patients consecutively admitted to our center with ST-segment elevation myocardial infarction undergoing a primary percutaneous coronary intervention. Clinical, ECG, and angiographic data were collected. We carried out univariate and multivariate analysis, using a combined endpoint of death, reinfarction, stroke, and clinically relevant bleeding. AF was documented in 117 patients. Among them, 25 presented AF at admission (previous AF) and 92 developed new-onset AF (66% transient, 13% persistent). Patients with AF were older, more frequently men, and had a worse Killip class, and a poorer left-ventricular ejection fraction. When analyzing the different types of AF, patients with new-onset AF (persistent and transient) had a higher Killip class and a worse left-ventricular ejection fraction. AF was associated with significantly higher in-hospital mortality and with a greater incidence of in-hospital adverse events. An increase in in-hospital mortality was recorded both for previous and for new-persistent AF, but after adjusting for confounding factors, only persistent AF was found to carry a worse short-term prognosis. CONCLUSION: In patients undergoing primary angioplasty in the stent era, AF is associated with a poor prognosis. This risk appears to be particularly high among patients with persistent AF. |
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Authors:
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Dafne Viliani; David Vivas; Monica Chung; María J Pérez-Vizcayno; Rosana Hernández-Antolín; Camino Bañuelos; Javier Escaned; Antonio Fernández-Ortiz; Pilar Jiménez-Quevedo; Isidre Vilacosta; Carlos Macaya; Fernando Alfonso |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-9-16 |
Journal Detail:
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Title: Coronary artery disease Volume: - ISSN: 1473-5830 ISO Abbreviation: Coron. Artery Dis. Publication Date: 2012 Sep |
Date Detail:
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Created Date: 2012-9-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9011445 Medline TA: Coron Artery Dis Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Cardiovascular Institute, San Carlos University Hospital, Madrid, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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