Document Detail

Prognosis for clinical pregnancy and birth after transferring embryos derived from a cohort of incompletely mature oocytes at retrieval time.
MedLine Citation:
PMID:  22850472     Owner:  NLM     Status:  In-Data-Review    
The purpose of this retrospective study was to establish a prognosis for implantation, pregnancy and live birth rates in stimulated IVF cycles after transferring embryos derived from: 1/ retrieved immature oocytes that matured overnight in vitro (late mature group: LM); 2/ retrieved immature oocytes that matured overnight in vitro and were added to the embryos derived from retrieved mature oocytes (mixed embryos group: MX); and 3/ retrieved mature oocytes (mature group: M). The obtained implantation, clinical pregnancy and live birth rates for the LM group were: 5.6%, 11.4%, 11.4%; for the MX group were: 4.2%, 14.6%, 11.6%; and for the M group were: 14.6%, 45.2% and 33.3%, respectively. These measurements were significantly lower p<0.05 for the LM and MX groups in comparison to the M group. The number of oocytes retrieved and the number of embryos transferred were the lowest (p<0.001-0.05) for the LM group. It is concluded, that the retrieved immature oocytes are able to mature during overnight culture in vitro, be fertilized and provide developmentally competent embryos with the prognosis of 11% for the successful delivery.
Teresa Wiesak; Anna T Grazul-Bilska; Maria Wikarczuk; Jay S Schinfeld; Larry I Barmat; Annette Lee; Stephen G Somkuti
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Reproductive biology     Volume:  12     ISSN:  1642-431X     ISO Abbreviation:  Reprod Biol     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-08-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101160559     Medline TA:  Reprod Biol     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  219-29     Citation Subset:  IM    
10-243 Olsztyn, Institute of Animal Reproduction and Food Science of Polish Academy of Science, Poland. e-mail:
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