| Prognosis of upper eyelid epiblepharon repair in down syndrome. | |
MedLine Citation:
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PMID: 20643394 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the recurrence rate after upper eyelid epiblepharon repair in patients with Down syndrome. DESIGN: Retrospective, observational study. METHODS: Total of 578 Korean children (21 with Down syndrome patients, 557 with non-Down syndrome patients), who had undergone epiblepharon repair and were followed up for more than 2 months, were included in this study. The recurrence rate was compared between two groups at 2, 6 months after surgery. Recurrence was defined as the re-appearance of cilia touching to cornea. The recurrence rate was also analyzed according to whether patients had undergone concomitant z-medial epicanthoplasty or not. RESULTS: Lower eyelid epiblepharon repair was performed on 22 eyelids of Down syndrome patients, and 1072 eyelids of non-Down syndrome patients. At 3 months after surgery, the recurrence rate was not significantly different between two groups (P = 1.00). Upper eyelid epiblepharon was repaired on 40 eyelids of Down syndrome patients, and 204 eyelids in non-Down syndrome patients. At 2 and 6 months after surgery, the recurrence rate was significantly higher in Down syndrome patients (27.5% and 29.4%) than non-Down syndrome patients (3.4% and 4.6%) (P = 0.000, P = 0.004, respectively). The recurrence rate of upper eyelid epiblepharon repair was not affected in both groups whether Z-epicanthoplasty was combined or not (P = 1.00 in both groups). CONCLUSIONS: In Down syndrome patients, the recurrence rate after upper eyelid epiblepharon repair was higher than non-Down syndrome patients. The effect of combined Z-medial epicanthoplasty was limited in both groups. |
Authors:
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Kyoung Min Lee; Ho Kyung Choung; Nam Ju Kim; Min Joung Lee; Kyeong-Wook Lee; Sang In Khwarg |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: American journal of ophthalmology Volume: 150 ISSN: 1879-1891 ISO Abbreviation: Am. J. Ophthalmol. Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-24 Completed Date: 2010-10-06 Revised Date: 2011-07-15 |
Medline Journal Info:
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Nlm Unique ID: 0370500 Medline TA: Am J Ophthalmol Country: United States |
Other Details:
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Languages: eng Pagination: 476-480.e1 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Child Down Syndrome / complications* Eye Abnormalities / diagnosis, surgery* Eyelids / abnormalities* Female Follow-Up Studies Humans Male Ophthalmologic Surgical Procedures* Prognosis Recurrence Retrospective Studies |
| Comments/Corrections | |
Comment In:
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Am J Ophthalmol. 2011 Jun;151(6):1104; author reply 1104-5
[PMID:
21616215
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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