Document Detail


Prognosis of Japanese encephalitis: a multivariate analysis.
MedLine Citation:
PMID:  9879695     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To evaluate the role of various clinical neurophysiological laboratory and radiological parameters in the prognosis of Japanese encephalitis (JE), 28 patients were prospectively evaluated. Their age ranged between two and 54 years, with eight of them being female and 11 children. The outcome was defined, at the end of a six-month period, as being poor (bed-ridden), partial (partial dependence for activity for daily life) and complete recovery (independent for activities of daily life). A number of clinical (age, degree of coma, decerebration or decortication and reflex changes), laboratory (CSF cell and protein content, and haemagglutination inhibition titre in the serum), neurophysiological (EEG, EMG, sensory and motor evoked potentials) and the extent of radiological changes were subjected to stepwise multivariate logistic regression analysis. By the end of six months, four patients had died, seven had poor, ten partial and seven had complete recovery. The best set of predictors of outcome included age, Glasgow coma scale and reflex changes.
Authors:
U K Misra; J Kalita; M Srivastava
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Journal of the neurological sciences     Volume:  161     ISSN:  0022-510X     ISO Abbreviation:  J. Neurol. Sci.     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1999-03-23     Completed Date:  1999-03-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375403     Medline TA:  J Neurol Sci     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  143-7     Citation Subset:  IM    
Affiliation:
Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. ukmisra@sgpgi.ren.nic.in
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Distribution
Child
Child, Preschool
Electroencephalography
Encephalitis, Japanese / diagnosis*,  physiopathology
Female
Humans
Logistic Models
Magnetic Resonance Imaging
Male
Middle Aged
Multivariate Analysis
Prognosis
Prospective Studies
Regression Analysis
Risk Factors
Tomography, X-Ray Computed
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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