Document Detail


Progestin receptor levels in endometria with delayed or incomplete secretory changes.
MedLine Citation:
PMID:  6621948     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In women with an infertility problem, cytosol progestin receptors were quantified in endometrial biopsies and correlated to histologic postovulatory dating. In 19 women (group A) the histologic dating corresponded to the cycle day; 14 women (group B) showed delayed or incomplete secretory changes. Group B showed significantly lower mean progestin receptor values (132 +/- 22 fmoles/mg protein [+/- SEM, P less than .01] ) than group A (236 +/- 29 fmoles/mg protein). The mean serum progesterone values did not differ significantly between groups A and B in the midluteal or the late luteal phase of the cycle. Inadequate maturation of the endometrium seems to correlate with insufficient development of progestin receptor binding sites rather than with decreased serum progesterone levels.
Authors:
T Laatikainen; B Andersson; J Kärkkäinen; T Wahlström
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  62     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1983-11-23     Completed Date:  1983-11-23     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  592-5     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Cytosol / analysis
Endometrium / analysis*,  physiopathology
Female
Humans
Infertility, Female / metabolism*,  physiopathology
Ovulation
Progesterone / blood
Receptors, Progesterone / analysis*,  metabolism
Chemical
Reg. No./Substance:
0/Receptors, Progesterone; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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