Document Detail


Progesterone receptor-mediated up-regulation of transthyretin in preimplantation mouse uterus.
MedLine Citation:
PMID:  20188365     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Transthyretin (TTR), a carrier for thyroxine and retinol, has its messenger RNA (mRNA) expressed in the glandular endometrial epithelium and its protein detected in the glandular endometrial epithelium and the uterine lumen. TTR mRNA is dramatically up-regulated in the preimplantation mouse uterus as well as the P-treated ovariectomized mouse uterus, and in both situations the up-regulation of TTR is blocked by treatment with the P receptor antagonist RU486.
Authors:
Honglu Diao; Shuo Xiao; Juan Cui; Jerold Chun; Ying Xu; Xiaoqin Ye
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-02-26
Journal Detail:
Title:  Fertility and sterility     Volume:  93     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-17     Completed Date:  2010-06-08     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2750-3     Citation Subset:  IM    
Copyright Information:
Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Affiliation:
Department of Physiology and Pharmacology, College of Veterinary Medicine, The University of Georgia, Athens, Georgia 30602, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Embryo Implantation
Female
Mice
Mice, Inbred C57BL
Mifepristone / pharmacology
Prealbumin / biosynthesis*
Pregnancy
Progesterone / pharmacology
Receptors, Lysophosphatidic Acid / genetics
Receptors, Progesterone / physiology*
Up-Regulation
Uterus / metabolism*
Grant Support
ID/Acronym/Agency:
R01 HD050685/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
0/LPAR5 protein, mouse; 0/Prealbumin; 0/Receptors, Lysophosphatidic Acid; 0/Receptors, Progesterone; 57-83-0/Progesterone; 84371-65-3/Mifepristone
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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