Document Detail

Progesterone autoimmune dermatitis with positive autologous serum skin test result.
MedLine Citation:
PMID:  21252802     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: : Progesterone autoimmune dermatitis is a rare disease attributable to hypersensitivity to endogenous progesterone and characterized by cyclic dermatologic manifestations at the end of the luteal phase that disappear some days after menses.
CASE: : A 35-year-old woman experienced cyclic premenstrual urticaria and angioedema occurring from 4 days before to 5 days after menses. The diagnosis of progesterone autoimmune dermatitis was made by a progesterone-positive skin test. Autologous serum skin test, using sera from estrogenic and luteal phases, also elicited a positive response. The patient became pregnant with near-clearance of the urticaria.
CONCLUSION: : Skin tests with progesterone and autologous serum, which are easy to perform, convenient, and inexpensive, are highly useful for establishing the diagnosis of progesterone autoimmune dermatitis and ruling out other skin disorders.
Pilar García-Ortega; Enrique Scorza
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  117     ISSN:  1873-233X     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  495-8     Citation Subset:  AIM; IM    
From the Allergy Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Spain.
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