| Progesterone at the picomolar range is a chemoattractant for mammalian spermatozoa. | |
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MedLine Citation:
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PMID: 16784744 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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By means of a videomicroscopy system and a computer image analysis, we performed chemotaxis assays to detect true chemotaxis in human spermatozoa, in parallel to immunohistochemistry detection of progesterone inside the cumulus cells. Progesterone indeed chemotactically guides mammalian spermatozoa at very low hormone concentrations, and the cumulus oophorus could be a potential place for sperm chemotaxis mediated by progesterone in vivo. |
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Authors:
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María Eugenia Teves; Flavia Barbano; Héctor Alejandro Guidobaldi; Raúl Sanchez; Werner Miska; Laura Cecilia Giojalas |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2006-06-19 |
Journal Detail:
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Title: Fertility and sterility Volume: 86 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2006 Sep |
Date Detail:
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Created Date: 2006-09-05 Completed Date: 2006-09-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 745-9 Citation Subset: IM |
Affiliation:
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Center for Cellular and Molecular Biology, Faculty of Sciences, National University of Córdoba, Córdoba, Argentina. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cells, Cultured Chemotactic Factors / administration & dosage Chemotaxis / drug effects, physiology* Dose-Response Relationship, Drug Humans Male Progesterone / administration & dosage* Sperm Motility / drug effects, physiology* Spermatozoa / cytology*, drug effects, physiology* |
| Chemical | |
Reg. No./Substance:
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0/Chemotactic Factors; 57-83-0/Progesterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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