Document Detail


Progesterone at the picomolar range is a chemoattractant for mammalian spermatozoa.
MedLine Citation:
PMID:  16784744     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
By means of a videomicroscopy system and a computer image analysis, we performed chemotaxis assays to detect true chemotaxis in human spermatozoa, in parallel to immunohistochemistry detection of progesterone inside the cumulus cells. Progesterone indeed chemotactically guides mammalian spermatozoa at very low hormone concentrations, and the cumulus oophorus could be a potential place for sperm chemotaxis mediated by progesterone in vivo.
Authors:
María Eugenia Teves; Flavia Barbano; Héctor Alejandro Guidobaldi; Raúl Sanchez; Werner Miska; Laura Cecilia Giojalas
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-06-19
Journal Detail:
Title:  Fertility and sterility     Volume:  86     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-09-05     Completed Date:  2006-09-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  745-9     Citation Subset:  IM    
Affiliation:
Center for Cellular and Molecular Biology, Faculty of Sciences, National University of Córdoba, Córdoba, Argentina.
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MeSH Terms
Descriptor/Qualifier:
Cells, Cultured
Chemotactic Factors / administration & dosage
Chemotaxis / drug effects,  physiology*
Dose-Response Relationship, Drug
Humans
Male
Progesterone / administration & dosage*
Sperm Motility / drug effects,  physiology*
Spermatozoa / cytology*,  drug effects,  physiology*
Chemical
Reg. No./Substance:
0/Chemotactic Factors; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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