| Progestagen-dependent effect on some plasma proteins during oral contraception. | |
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MedLine Citation:
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PMID: 2967233 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Seventeen healthy women received a combination of 0.030 mg of ethinyl estradiol and 0.150 mg of levonorgestrel or a combination of 0.030 mg of ethinyl estradiol and 0.150 mg of desogestrel for 2 years as oral contraception. Serum levels of sex hormone binding globulin, transcortin, ceruloplasmin, and pregnancy-associated protein were measured before contraception, during 3, 6, 12, 18, and 24 months of treatment, and 2 months after stopping the pill. Oral contraception with both preparations induced a similar, significant rise in both ceruloplasmin and pregnancy-associated protein. Sex hormone binding globulin levels rose significantly with the ethinyl estradiol-desogestrel, but not with the ethinyl estradiol-levonorgestrel combination. Transcortin increased with both preparations, more with the ethinyl estradiol-desogestrel combination. |
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Authors:
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P Liukko; R Erkkola; E W Bergink |
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39813 - Intrauterine devices: medicated and nonmedicated. 16488003 - Contraception for population control in exotic carnivores. 576383 - Limitations of visualization of the entire fetus by means of second-trimester fetoscopy. |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Gynecologic and obstetric investigation Volume: 25 ISSN: 0378-7346 ISO Abbreviation: Gynecol. Obstet. Invest. Publication Date: 1988 |
Date Detail:
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Created Date: 1988-07-01 Completed Date: 1988-07-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7900587 Medline TA: Gynecol Obstet Invest Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 118-22 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, University Central Hospital of Turku, Finland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Proteins
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analysis* Ceruloplasmin / blood Contraceptives, Oral, Combined / pharmacology* Desogestrel Ethinyl Estradiol / pharmacology* Female Humans Levonorgestrel Norgestrel / pharmacology Norpregnenes / pharmacology Pregnancy Proteins / blood Progesterone Congeners / pharmacology* Sex Hormone-Binding Globulin / blood Transcortin / blood |
| Chemical | |
Reg. No./Substance:
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0/Blood Proteins; 0/Contraceptives, Oral, Combined; 0/Norpregnenes; 0/Pregnancy Proteins; 0/Progesterone Congeners; 0/Sex Hormone-Binding Globulin; 54024-22-5/Desogestrel; 57-63-6/Ethinyl Estradiol; 6533-00-2/Norgestrel; 797-63-7/Levonorgestrel; 9010-38-2/Transcortin; EC 1.16.3.1/Ceruloplasmin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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