| Progenitors in motion: mechanisms of mobilization of endothelial progenitor cells. | |
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MedLine Citation:
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PMID: 19843051 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Endothelial progenitor cells are a population of bone marrow-derived mononuclear cells thought to engage in endothelial repair and hence are considered potential therapeutic agents in many pathological conditions. The mechanism of their exit from the bone marrow to the circulation and damaged tissues, termed mobilization, has not been fully elucidated. Despite this, several pharmacological interventions have been shown to influence mobilization of these specialized cells. Here we review the current understanding of their mobilization. |
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Authors:
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Lindsey Tilling; Philip Chowienczyk; Brian Clapp |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: British journal of clinical pharmacology Volume: 68 ISSN: 1365-2125 ISO Abbreviation: Br J Clin Pharmacol Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-10-21 Completed Date: 2010-07-30 Revised Date: 2010-10-04 |
Medline Journal Info:
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Nlm Unique ID: 7503323 Medline TA: Br J Clin Pharmacol Country: England |
Other Details:
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Languages: eng Pagination: 484-92 Citation Subset: IM |
Affiliation:
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King's College London, London SE1 7EH, UK. lindsey.tilling@kcl.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bone Marrow Cells
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metabolism,
physiology* Cardiovascular Diseases / pathology Cell Movement / physiology* Cytokines / metabolism* Endothelial Cells / metabolism, physiology* Humans Interleukin-8 Nitric Oxide Stem Cells / metabolism, physiology* |
| Chemical | |
Reg. No./Substance:
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0/Cytokines; 0/Interleukin-8; 10102-43-9/Nitric Oxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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