Document Detail

Profound hypothermia with circulatory arrest: nine years' clinical experience.
MedLine Citation:
PMID:  7087543     Owner:  NLM     Status:  MEDLINE    
A total of 550 intracardiac operations were performed with the aid of profound hypothermia and circulatory arrest between March, 1971, and December, 1979. Both cooling and rewarming were effected by means of an extracorporeal heat exchanger. Overall mortality was 20%, falling to 10% in 1979. Highest risks were associated with operations in the neonatal period and for unusually complex defects. The technique has proved safe for straight forward corrections in young age groups and is especially valuable for selected complex lesions in older children and those requiring reoperation. Although circulatory arrest has greatly extended the range of corrective heart operation in infancy, we believe there is still a significant place for palliative procedures in appropriate circumstances. Neurologic complications attributed to the technique have been uncommon, and only 4.5% of the survivors have any recognizable residual neurologic lesion, whether coincidental or resulting from circulatory arrest. The technique is simple, reliable, and generally safe.
J Tharion; D C Johnson; J M Celermajer; R M Hawker; T B Cartmill; J H Overton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of thoracic and cardiovascular surgery     Volume:  84     ISSN:  0022-5223     ISO Abbreviation:  J. Thorac. Cardiovasc. Surg.     Publication Date:  1982 Jul 
Date Detail:
Created Date:  1982-08-26     Completed Date:  1982-08-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376343     Medline TA:  J Thorac Cardiovasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  66-72     Citation Subset:  AIM; IM    
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MeSH Terms
Child, Preschool
Heart Arrest, Induced* / methods,  mortality
Heart Defects, Congenital / surgery*
Heart Septal Defects, Ventricular / surgery
Hypothermia, Induced* / methods
Tetralogy of Fallot / surgery
Transposition of Great Vessels / surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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