Document Detail


Profiling Cellular Myristoylation and Palmitoylation Using ω-Alkynyl Fatty Acids.
MedLine Citation:
PMID:  21964784     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Methods to detect and characterize cellular protein myristoylation and palmitoylation are invaluable in cell biology, immunology, and virology. Recently, we developed ω-alkynyl fatty acid probes for monitoring myristoylation and palmitoylation of cellular proteins. This article describes a biochemical procedure for metabolic labeling of cells with ω-alkynyl fatty acids and click chemistry.
Authors:
Rami N Hannoush
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  800     ISSN:  1940-6029     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2012  
Date Detail:
Created Date:  2011-10-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  85-94     Citation Subset:  IM    
Affiliation:
Department of Early Discovery Biochemistry, Genentech, Inc., South San Francisco, CA, USA, hannoush.rami@gene.com.
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