| Profilin phosphorylation as a VEGFR effector in angiogenesis. | |
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MedLine Citation:
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PMID: 23033049 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Vascular endothelial growth factor (VEGF) signalling induces embryonic vascular development and angiogenesis in adult tissues. Direct phosphorylation of the actin-binding protein profilin by VEGF receptors is now shown to increase its affinity for actin, and to be essential for adult but not embryonic arteriogenesis. |
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Authors:
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Michael Simons; Martin A Schwartz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Nature cell biology Volume: 14 ISSN: 1476-4679 ISO Abbreviation: Nat. Cell Biol. Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100890575 Medline TA: Nat Cell Biol Country: England |
Other Details:
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Languages: eng Pagination: 985-7 Citation Subset: IM |
Affiliation:
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Yale Cardiovascular Research Center, Section Of Cardiovascular Medicine, Department of Internal Medicine and Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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