Document Detail


Profiles enriched in GABA-like immunoreactivity participate in serial synapses in the pontine nuclei of baboon (Papio anubis).
MedLine Citation:
PMID:  2612606     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Using a postembedding immunogold procedure with an antiserum against glutaraldehyde-fixed GABA, we demonstrate GABA-like immunoreactivity in two classes of synaptic profiles in the pontine nuclei of baboon. One is an axon terminal in symmetrical synaptic contact with small or medium-sized GABA-immunonegative dendrites, the other is a pale, vesicle-containing profile resembling a dendrite or dendritic process which participates in serial synaptic arrangements. These synaptic arrangements, or triads, consist of a GABA-like immunoreactive, pale vesicle-containing profile being postsynaptic to a GABA-immunonegative axon terminal, and presynaptic to a small or medium-sized GABA-immunonegative dendrite. In at least some of these triads, the GABA-immunonegative axon terminals also contact the GABA-immunonegative dendrite directly.
Authors:
J E Aas; O P Ottersen; P Brodal
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Experimental brain research     Volume:  78     ISSN:  0014-4819     ISO Abbreviation:  Exp Brain Res     Publication Date:  1989  
Date Detail:
Created Date:  1990-03-01     Completed Date:  1990-03-01     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  0043312     Medline TA:  Exp Brain Res     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  641-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Immunohistochemistry
Papio / anatomy & histology,  metabolism*
Pons / cytology,  metabolism*
Synapses / metabolism*,  ultrastructure
gamma-Aminobutyric Acid / metabolism*,  physiology
Chemical
Reg. No./Substance:
56-12-2/gamma-Aminobutyric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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