Document Detail

Production of tetrodotoxin in puffer fish embryos.
MedLine Citation:
PMID:  21781897     Owner:  NLM     Status:  In-Data-Review    
It has been accepted that puffer fish accumulates tetrodotoxin through the food chain. This indicates that tetrodotoxin in puffer fish is exogenous. The present study, however, describes an endogenous origin of tetrodotoxin in puffer fish. For this purpose, the ovulated oocytes from puffer fish Fugu niphobles were artificially fertilized and cultivated. The toxin levels of embryos increased gradually with development until the time of hatching, suggesting that the increased toxin is a product of embryos.
K Matsumura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Environmental toxicology and pharmacology     Volume:  6     ISSN:  1382-6689     ISO Abbreviation:  Environ. Toxicol. Pharmacol.     Publication Date:  1998 Dec 
Date Detail:
Created Date:  2011-07-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9612020     Medline TA:  Environ Toxicol Pharmacol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  217-9     Citation Subset:  -    
Yamaguchi Prefectural Research Institute of Health, 2-5-67 Aoi, Yamaguchi 753-0821, Japan.
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