Document Detail


Production of reference enteroviruses.
MedLine Citation:
PMID:  4300898     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Forty-five human enterovirus reagents of certified purity and quality were prepared for use as seed viruses and as immunizing antigens. One of the reagents was ampouled as "untreated" seed virus, whereas 14 were ampouled as "MgCl(2)-stabilized" reagents. The remaining 30 reagents were ampouled as "untreated" seed viruses and as "MgCl(2)-stabilized" reagents. Thirty of the reagents were propagated on primary African green monkey kidney cells, 3 on primary baboon kidney cells, 3 on primary rhesus monkey kidney cells, and the remaining 9 on human amnion cells. Forty-two of the viral antigens were concentrated for use in the production of high-titered specific antisera in large animals.
Authors:
S S Kalter; A R Rodriguez; V Armour
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Applied microbiology     Volume:  16     ISSN:  0003-6919     ISO Abbreviation:  Appl Microbiol     Publication Date:  1968 Oct 
Date Detail:
Created Date:  1968-12-08     Completed Date:  1968-12-08     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7605802     Medline TA:  Appl Microbiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1575-83     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Biological Products / standards
Enterovirus*
Enterovirus B, Human*
Neutralization Tests
Poliovirus*
Chemical
Reg. No./Substance:
0/Biological Products
Comments/Corrections

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