Document Detail

Production of ketocarotenoids by microalgae.
MedLine Citation:
PMID:  10341427     Owner:  NLM     Status:  MEDLINE    
Among the highly valued ketocarotenoids employed for food coloration, astaxanthin is probably the most important. This carotenoid may be produced biotechnologically by a number of microorganisms, and the most promising seems to be the freshwater flagellate Haematococcus pluvialis (Chlorophyceae), which accumulate astaxanthin in their aplanospores. Many physiological aspects of the transition of the flagellate into aplanospores have been described. Mixotrophic cultivation and suitable irradiance may result in fairly good yields (up to 40 mg/l; 43 mg/g cell dry weight) within a reasonable time, under laboratory conditions. In order to compete with synthetic astaxanthin, suitable scaling-up is required. However, large-scale production in open ponds has proved unsatisfactory because of severe contamination problems. A selective medium might overcome this difficulty. Further research for the development of suitable strains is thus warranted.
P Z Margalith
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Applied microbiology and biotechnology     Volume:  51     ISSN:  0175-7598     ISO Abbreviation:  Appl. Microbiol. Biotechnol.     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-07-13     Completed Date:  1999-07-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8406612     Medline TA:  Appl Microbiol Biotechnol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  431-8     Citation Subset:  IM    
Department of Food Engineering and Biotechnology, Technion, Israel Institute of Technology, Haifa, Israel.
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MeSH Terms
Algae, Green / genetics,  growth & development,  metabolism*
Basidiomycota / growth & development,  metabolism
Carotenoids / biosynthesis*
beta Carotene / analogs & derivatives*,  biosynthesis
Reg. No./Substance:
0/Xanthophylls; 36-88-4/Carotenoids; 472-61-7/astaxanthine; 7235-40-7/beta Carotene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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